Asymmetric palladium-catalyzed benzylic nucleophilic substitution:: high enantioselectivity with the DUPHOS family ligands

被引：29
|
作者：
Assié, M [1 ]
Legros, JY [1 ]
Fiaud, JC [1 ]
机构：
[1] Univ Paris 11, Inst Chim Mol & Mat Orsay, CNRS, UMR 8075,Lab Catalyse Mol, F-91405 Orsay, France
来源：
TETRAHEDRON-ASYMMETRY | 2005年 / 16卷 / 06期
关键词：
D O I：
10.1016/j.tetasy.2005.01.032
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The asymmetric palladium-catalyzed benzylic reaction of 1-(2-naphthyl)ethyl acetate and its 6-methoxy substituted analogue with dimethyl malonate anion led to substitution products with up to 90% ee when the iPr-DUPHOS chiral ligand was used. (C) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1183 / 1187
页数：5
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