Beyond depression: Other uses for tricyclic antidepressants

被引：48
|
作者：
Schneider, Joanne [1 ]
Patterson, Mary [1 ]
Jimenez, Xavier F. [1 ,2 ]
机构：
[1] Cleveland Clin, Neurol Inst, Ctr Comprehens Pain Recovery, Cleveland, OH 44195 USA
[2] Case Western Reserve Univ, Cleveland Clin, Lerner Coll Med, Cleveland, OH 44106 USA
来源：
CLEVELAND CLINIC JOURNAL OF MEDICINE | 2019年 / 86卷 / 12期
关键词：
BACK-PAIN; MANAGEMENT; FIBROMYALGIA; SYMPTOMS; MEDICATIONS; INSOMNIA;
D O I：
10.3949/ccjm.86a.19005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Tricyclic antidepressants (TCAs) were originally designed and marketed for treating depression, but over time they have been applied to a variety of conditions, mostly off-label. TCAs can serve as first-line or augmenting drugs for neuropathic pain, headache, migraine, gastrointestinal syndromes, fibromyalgia, pelvic pain, insomnia, and psychiatric conditions other than depression. This article reviews pharmacology, dosing, and safety considerations for these uses.
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页码：807 / 814
页数：8
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