A protocell with fusion and division

被引:10
|
作者
Xu, Bo-Ying [1 ]
Xu, Jian [1 ]
Yomo, Tetsuya [1 ]
机构
[1] East China Normal Univ, Biomed Synthet Biol Res Ctr, Sch Life Sci, Inst Biol & Informat Sci, Shanghai 200062, Peoples R China
关键词
GIANT UNILAMELLAR VESICLES; MEMBRANE-FUSION; ARTIFICIAL CELL; PHOSPHOLIPID-VESICLES; MORPHOLOGICAL-CHANGES; PROTEIN EXPRESSION; SELF-REPRODUCTION; LIPOSOMES; GROWTH; STEP;
D O I
10.1042/BST20190576
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A protocell is a synthetic form of cellular life that is constructed from phospholipid vesicles and used to understand the emergence of life from a nonliving chemical network. To be considered 'living', a protocell should be capable of self-proliferation, which includes successive growth and division processes. The growth of protocells can be achieved via vesicle fusion approaches. In this review, we provide a brief overview of recent research on the formation of a protocell, fusion and division processes of the protocell, and encapsulation of a defined chemical network such as the genetic material. We also provide some perspectives on the challenges and future developments of synthetic protocell research.
引用
收藏
页码:1909 / 1919
页数:11
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