Meningeal leishmaniosis induced by Leishmania infantum in naturally infected dogs

被引:49
|
作者
Viñuelas, J
García-Alonso, M [1 ]
Ferrando, L
Navarrete, I
Molano, I
Mirón, C
Carcelén, J
Alonso, C
Nieto, CG
机构
[1] Univ Extremadura, Fac Vet, Dept Med & Sanidad Anim, Caceres 10071, Spain
[2] Hosp San Pedro Alcantara, Dept Microbiol, Caceres, Spain
[3] Hosp San Pedro Alcantara, Dept Anat Patol, Caceres, Spain
[4] Univ Autonoma Madrid, CSIC, Ctr Biol Mol Severo Ochoa, E-28049 Madrid, Spain
关键词
Leishmania infantum; dog; meningitis;
D O I
10.1016/S0304-4017(01)00413-7
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
We report two cases of meningitis caused by Leishmania infantum in naturally infected dogs. In both of these dogs the typical phenotypic features of granulomatous meningitis were observed with important lympho-plasma-cellular infiltrates and the presence of large numbers of parasites inside and outside macrophages. The immunological study of the cerebrospinal fluid of both animals showed that a large number of protein bands were recognized by those fluids and that they were similar to the ones recognized by the sera from the same animals. To our knowledge, this is the first description of meningitis associated to leishmaniosis. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:23 / 27
页数:5
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