NON-CYTOLYTIC HY-SPECIFIC CD4+T CELLS MEDIATE A STRONG GRAFT-VERSUS-LEUKEMIA EFFECT VIA CXCR4 DOWN-REGULATION ON TARGET CELLS

被引：0
|
作者：
Bondanza, Attilio [1 ]
Hambach, Lothar [2 ]
Aghai, Zohara [3 ]
Casucci, Monica [1 ]
Camisa, Barbara [1 ]
Fleischhauer, Katharina [1 ]
Nijmeijer, Bart [4 ]
Ciceri, Fabio [1 ]
Bonini, Chiara [1 ]
Goulmy, Els [3 ]
机构：
[1] Ist Sci San Raffaele, I-20132 Milan, Italy
[2] Hannover Med Sch, D-3000 Hannover, Germany
[3] Leiden Univ, Med Ctr, Leiden, Netherlands
[4] Amsterdam Mol Therapy, Amsterdam, Netherlands
来源：
TISSUE ANTIGENS | 2012年 / 79卷 / 06期
关键词：
D O I：
暂无
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：404 / 404
页数：1
相关论文
共 50 条
  • [21] Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
    Trenado, A
    Charlotte, F
    Fisson, S
    Yagello, M
    Klatzmann, D
    Salomon, BL
    Cohen, AL
    JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (11): : 1688 - 1696
  • [22] PMA-treated K-562 leukemia cells mediate a TH2-specific expansion of CD4+T cells in vitro
    Baker, EJ
    Ichiki, AT
    Hodge, JW
    Sugantharaj, D
    Bamberger, EG
    Lozzio, CB
    LEUKEMIA RESEARCH, 2000, 24 (12) : 1049 - 1057
  • [23] CD28 costimulation independence of target organ versus circulating memory antigen-specific CD4+T cells
    Fontenot, AP
    Gharavi, L
    Bennett, SR
    Canavera, SJ
    Newman, LS
    Kotzin, BL
    FASEB JOURNAL, 2003, 17 (07): : C213 - C213
  • [24] Host-reactive donor CD8+T memory stem cells but not mature T memory cells primed against leukemic cells mediate potent graft-versus-leukemia effect.
    Hexner, Elizabeth O.
    Frank, Dale
    Emerson, Stephen G.
    Zhang, Yi
    BLOOD, 2006, 108 (11) : 60A - 60A
  • [25] Interleukin-12 preserves the graft-versus-leukemia effect of allogeneic CD8 T cells while inhibiting CD4-dependent graft-versus-host disease in mice
    Yang, YG
    Sergio, JJ
    Pearson, DA
    Szot, GL
    Shimizu, A
    Sykes, M
    BLOOD, 1997, 90 (11) : 4651 - 4660
  • [26] CD8+ central memory T cells mediate graft-ve rsus- host disease although retain graft-versus-leukemia effect.
    Zheng, H
    Matte, CC
    Anderson, BE
    Venkatesan, S
    Jain, D
    Shlomchik, MJ
    Shlomchik, WD
    BLOOD, 2005, 106 (11) : 381A - 381A
  • [27] Next-generation sequencing reveals broad down-regulation of microRNAs in secondary progressive multiple sclerosis CD4+T cells
    Sanders, Katherine A.
    Benton, Miles C.
    Lea, Rod A.
    Maltby, Vicki E.
    Agland, Susan
    Griffin, Nathan
    Scott, Rodney J.
    Tajouri, Lotti
    Lechner-Scott, Jeannette
    CLINICAL EPIGENETICS, 2016, 8
  • [28] Transcriptional mechanisms of CXCR4 down-regulation induced in cells infected with the CD4-independent X4 HIV-1 isolate m7NDK
    Valente, S
    Delcroix, D
    Ley, B
    Briand, P
    Hazan, U
    6TH EUROPEAN CONFERENCE ON EXPERIMENTAL AIDS RESEARCH, 2001, : 61 - 68
  • [29] Down-regulation of CXCR4 expression by SDF-KDEL in CD34+ hematopoietic stem cells: An anti-human immunodeficiency virus strategy
    Zhang, Jiu-Cong
    Sun, Li
    Nie, Qing-He
    Huang, Chang-Xing
    Jia, Zhan-Sheng
    Wang, Jiu-Ping
    Lian, Jian-Qi
    Li, Xin-Hong
    Wang, Ping-Zhong
    Zhang, Ye
    Zhuang, Yan
    Sun, Yong-Tao
    Bai, Xuefan
    JOURNAL OF VIROLOGICAL METHODS, 2009, 161 (01) : 30 - 37
  • [30] CD4+ bias in T cells cloned from a CML patient with active graft versus leukemia effect
    Dodi, IA
    Van Rhee, F
    Forde, HC
    Roura-Mir, C
    Jaraquemada, D
    Goldman, JM
    Madrigal, JA
    CYTOTHERAPY, 2002, 4 (04) : 353 - 363
12345