Failure of high-dose chemotherapy with peripheral blood stem cell support for refractory placental site trophoblastic tumor

被引：10
|
作者：
Aoki, Y [1 ]
Kodama, S [1 ]
Kurata, H [1 ]
Kase, H [1 ]
Tanaka, K [1 ]
机构：
[1] Niigata Univ, Sch Med, Dept Obstet & Gynecol, Niigata 9518510, Japan
来源：
GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 1999年 / 47卷 / 03期
关键词：
placental site trophoblastic tumor; high-dose chemotherapy; peripheral blood stem cell transplantation;
D O I：
10.1159/000010081
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Placental site trophoblastic tumor(PSTT) is a rare form of gestational trophoblastic disease. The metastatic and refractory cases have a very poor prognosis. To our knowledge, this is the first report of the application of high-dose chemotherapy with autologous peripheral blood stem cell transplantation (PBSCT) for the treatment of refractory metastatic PSTT. A 36-year-old woman had a metastatic PSTT refractory to several:lines of chemotherapy. She was treated with high dose of carboplatin and etoposide with:autologous PBSCT. She showed only a temporary response to high-dose chemotherapy with PBSCT support and died of disease.
引用
收藏
页码：214 / 216
页数：3
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