The balance of mucosal CD4 T cells prior to infection is associated with control of virus replication after therapeutic vaccination in SIV-infected rhesus macaques

被引：0
|
作者：
Tunggal, H. [1 ,2 ]
Munson, P. [1 ,2 ]
O'Connor, M. [1 ,2 ]
Bratt, D. [2 ]
Hajari, N. [2 ]
Wangari, S. [2 ]
May, D. [2 ]
Agricola, B. [2 ]
Smedley, J. [2 ]
Bagley, K. [3 ,4 ]
Fuller, D. [1 ,2 ]
机构：
[1] Univ Washington, Microbiol, Seattle, WA 98195 USA
[2] Washington Natl Primate Res Ctr, Seattle, WA USA
[3] Profectus Biosci, Baltimore, MD USA
[4] Orlance Inc, Seattle, WA USA
来源：
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY | 2021年 / 24卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
OAA0403
引用
收藏
页码：10 / 11
页数：2
相关论文
共 50 条
  • [41] Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+T cells in germinal centers of rhesus macaques
    Eichholz, K.
    Fukazawa, Y.
    Peterson, C. W.
    Haeseleer, F.
    Medina, M.
    Hoffmeister, S.
    Duell, D.
    Varco-Merth, B.
    Dross, S.
    Park, H.
    Labriola, C.
    Axthelm, M.
    Murane, R. D.
    Smedley, J. V.
    Jin, L.
    Rust, B. J.
    Fuller, D. H.
    Kiem, H. -P.
    Picker, L. J.
    Okoye, A. A.
    Corey, L.
    HIV MEDICINE, 2023, 24 : 345 - 345
  • [42] Anti-PD-1 Chimeric Antigen Receptor T Cells Efficiently Target SIV-Infected CD4+T Cells in Germinal Centers of Rhesus Macaques
    Eichholz, Karsten
    Fukazawa, Yoshinori
    Peterson, Christopher W.
    Haeseleer, Francoise
    Medina, Manuel
    Hoffmeister, Shelby
    Duell, Derick
    Varco-Merth, Benjamin
    Dross, Sandra
    Park, Haesun
    Labriola, Caralyn
    Axthelm, Michael
    Murane, Robert
    Smedley, Jeremy
    Jin, Lei
    Blake, Rust
    Fuller, Deborah
    Kiem, Hans-Peter
    Picker, Louis J.
    Okoye, Afam
    Corey, Larry
    MOLECULAR THERAPY, 2023, 31 (04) : 424 - 424
  • [43] Anti-PD-1 chimeric antigen receptor T cells efficiently target SIV-infected CD4+ T cells in germinal centres of rhesus macaques
    Eichholz, K.
    Fukazawa, Y.
    Peterson, C.
    Haeseleer, F.
    Medina, M.
    Hoffmeister, S.
    Duell, D.
    Varco-Merth, B.
    Dross, S.
    Park, H.
    Labriola, C.
    Axthelm, M.
    Murane, R.
    Smedley, J.
    Jin, L.
    Rust, B.
    Fuller, D.
    Kiem, H. P.
    Picker, L.
    Okoye, A.
    Corey, L.
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2023, 26
  • [44] CYTOKINE PRODUCTION AND CD45 ISOFORM EXPRESSION BY CD8+ T-CELLS ISOLATED FROM SIV-INFECTED RHESUS MACAQUES
    DIFABIO, S
    KANG, DW
    MARINARO, M
    MILLER, C
    MCGHEE, JR
    FUJIHASHI, K
    KIYONO, H
    FASEB JOURNAL, 1994, 8 (04): : A494 - A494
  • [45] Reactivation of Simian Varicella Virus in Rhesus Macaques after CD4 T Cell Depletion
    Traina-Dorge, Vicki
    Palmer, Brent E.
    Coleman, Colin
    Hunter, Meredith
    Frieman, Amy
    Gilmore, Anah
    Altrock, Karen
    Doyle-Meyers, Lara
    Nagel, Maria A.
    Mahalingam, Ravi
    JOURNAL OF VIROLOGY, 2019, 93 (03)
  • [46] Global dysfunction of CD4 T-lymphocyte cytokine expression in simian-human immunodeficiency virus/SIV-infected monkeys is prevented by vaccination
    McKay, PF
    Barouch, DH
    Schmitz, JE
    Veazey, RS
    Gorgone, DA
    Lifton, MA
    Williams, KC
    Letvin, NL
    JOURNAL OF VIROLOGY, 2003, 77 (08) : 4695 - 4702
  • [47] CD4 AND CD8 T-CELLS FROM SIV-INFECTED MACAQUES HAVE DEFECTIVE SIGNALING RESPONSES AFTER PERTURBATION OF EITHER CD3 OR CD2 RECEPTORS
    GALE, MJ
    LEDBETTER, JA
    SCHIEVEN, GL
    JONKER, M
    MORTON, WR
    BENVENISTE, RE
    CLARK, EA
    INTERNATIONAL IMMUNOLOGY, 1990, 2 (09) : 849 - 858
  • [48] Anti-CAR Antibody Detected after Infusion of Autologous CD4-MBL-CAR/CXCR5 CAR T Cells in SIV-Infected Rhesus Macaques
    Davey, Brianna C.
    Cartwright, Emily K.
    Pampusch, Mary S.
    Skinner, Pamela J.
    MOLECULAR THERAPY, 2021, 29 (04) : 362 - 362
  • [49] BCG-vaccination in SIV-infected infant macaques is associated with enhanced B cell, myeloid dendritic cell and CD4+T cell activation
    Wood, Matthew P.
    Wood, Lianna
    Sodora, Donald L.
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [50] Despite early antiretroviral therapy effector memory and follicular helper CD4 T cells are major reservoirs in visceral lymphoid tissues of SIV-infected macaques
    Rabezanahary, Henintsoa
    Moukambi, Felicien
    Palesch, David
    Clain, Julien
    Racine, Gina
    Andreani, Guadalupe
    Benmadid-Laktout, Ghita
    Zghidi-Abouzid, Ouafa
    Soundaramourty, Calayselvy
    Tremblay, Cecile
    Silvestri, Guido
    Estaquier, Jerome
    MUCOSAL IMMUNOLOGY, 2020, 13 (01) : 149 - 160
12345