Acute DeBakey Type I aortic dissection without intimal tear in the arch: is total arch replacement the right choice?

被引:12
|
作者
Colli, Andrea [1 ]
Carrozzini, Massimiliano [1 ]
Francescato, Annalisa [1 ]
Galuppo, Marco [1 ]
Comisso, Marina [1 ]
Toto, Francesca [1 ]
Gregori, Dario [2 ]
Gerosa, Gino [1 ]
机构
[1] Univ Padua, Dept Cardiac Thorac & Vasc Sci, Cardiac Surg Unit, Padua, Italy
[2] Univ Padua, Dept Cardiac Thorac & Vasc Sci, Biostat Epidemiol & Publ Hlth Unit, Padua, Italy
关键词
Aortic dissection; Intimal tear; Aortic arch; Total arch replacement; SURGERY STUDY-GROUP; A DISSECTION; HEMIARCH REPLACEMENT; OPERATIVE STRATEGY; ELEPHANT TRUNK; FALSE LUMEN; REPAIR; MANAGEMENT; MORTALITY; REGISTRY;
D O I
10.1093/icvts/ivx229
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVES: Surgical management of acute DeBakey Type I aortic dissection without intimal tear in the aortic arch is controversial. This study compared short- and long-term outcomes of total arch replacement (TAR) versus limited ascending aorta/hemiarch replacement (no-TAR) in a consecutive series of patients. METHODS: Between January 1998 and December 2015, 220 consecutive patients were operated for DeBakey Type I acute aortic dissection; 135 cases did not exhibit an intimal entry tear in the aortic arch and were subsequently selected to comprise the primary study cohort. A secondary subgroup analysis was made within these 135 cases, which comprised patients who received antegrade cerebral perfusion as the neuroprotective strategy of choice (n = 45). RESULTS: Mean follow-up period was 5 +/- 4 years. Among the patients selected, 21 (16%) underwent TAR. Thirty-day mortality was higher in the TAR group (38% vs 21%, P = 0.04). Postoperative complication rates were similar between the groups (61% vs 73%, P = 0.31). Long-term mortality and late aortic reintervention rates were also similar (7% vs 30%, P = 0.36 and 27% vs 14%, P = 0.32, respectively). From the subgroup of patients with antegrade cerebral perfusion, 14 (31%) underwent TAR and 31 (69%) had no-TAR. Mean follow-up-time was 3 +/- 2 years. Thirty-day mortality was higher in the TAR group (50% vs 16%, P < 0.01), postoperative complications, long-term mortality and late aortic reintervention rates were similar (64% vs 69%, P = 0.73; 0% vs 19%, P = 0.22; 29% vs 8%, P = 0.17, respectively). CONCLUSIONS: TAR was associated with higher 30-day mortality compared with the less extensive hemiarch replacement. In the long term, TAR showed a trend of improved survival and higher reintervention rate.
引用
收藏
页码:84 / 90
页数:7
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