1-{1-[2,8-Bis(trifluoromethyl)-4-quinolyl]-5-methyl-1H-1,2,3-triazol-4-yl}ethanone

被引:2
|
作者
Devarajegowda, H. C. [1 ]
Jeyaseelan, S. [1 ]
Sumangala, V. [2 ]
Bojapoojary [3 ]
Nayak, Suresh P. [3 ]
机构
[1] Univ Mysore, Dept Phys, Yuvarajas Coll, Mysore 570005, Karnataka, India
[2] Sequent Sci India Ltd, Baikampadi Mangalore, Karnataka, India
[3] Mangalore Univ, Dept Chem, Mangalagangothri 574199, Karnataka, India
关键词
GROWTH-INHIBITION; TRIAZOLES; AGENTS;
D O I
10.1107/S1600536810034926
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
There are two independent molecules in the asymmetric unit of the title compound, C(16)H(10)F(6)N(4)O. The triazole ring is not coplanar with the quinoline ring system; the dihedral angle between the two planes being 74.47 (12) and 63.97 (13)degrees in the two molecules. The crystal structure is characterized by intermolecular C-H center dot center dot center dot F, C-H center dot center dot center dot N and C-H center dot center dot center dot O hydrogen bonding. Weak intramolecular C-H center dot center dot center dot F interactions are observed. Disorder is observed in two F atoms of one of the trifluoromethyl groups of one independent molecule [ occupancy ratios 0.77 (3): 0.23 (3) and 0.77 (4): 0.23 (4)] and in all three F atoms of one of the trifluoromethyl groups of the second independent molecule [ occupancy ratios 0.520 (14): 0.480 (14), 0.615 (17): 0.385 (17) and 0.783 (11): 0.217 (11)]. The O atom is also disordered over two positions with occupancies of 0.60 (13) and 0.40 (13) in the first molecule.
引用
收藏
页码:O2512 / U37
页数:15
相关论文
共 50 条
  • [41] A 1:1 cocrystal of 2,8-bis(trifluoromethyl)quinolin-4-ol and 2,8-bis(trifluoromethyl)quinolin-4(1H)-one
    Sarojini, B. K.
    Narayana, B.
    Mayekar, Anil N.
    Yathirajan, H. S.
    Bolte, Michael
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O4478 - U4930
  • [42] The 2-((4-Amino-5-((2,4-dichlorophenoxy)methyl)-4H-1,2,4-triazol-3-yl)thio)-1-(5-methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)ethan-1-one
    Abdel-Wahab, Bakr F.
    Mabied, Ahmed F.
    Fettinger, James C.
    Farahat, Abdelbasset A.
    [J]. MOLBANK, 2023, 2023 (03)
  • [43] Design and Synthesis of Novel 1-((1-Phenyl-1H-1,2,3-triazol-4-yl)methyl)pyridin-2(1H)-one Derivatives
    Keskin, Selbi
    [J]. CHEMISTRYSELECT, 2023, 8 (32):
  • [44] (E)-1-(5-Methyl-1-(4-nitrophenyl)-1H-1,2,3-triazol-4-yl)-3-(naphthalen-2-yl)prop-2-en-1-one
    Kariuki, Benson M.
    Abdel-Wahab, Bakr F.
    Mohamed, Hanan A.
    El-Hiti, Gamal A.
    [J]. MOLBANK, 2022, 2022 (04)
  • [45] SYNTHESIS OF (2E, 3E)-1-[1-(1-ARYL-5-METHYL-1H-1,2,3-TRIAZOL-4-YL) ETHYLIDENE]-2-(4-OXO-THIAZOLIDIN-2-YLIDENE) HYDRAZINES
    Wang, Hui-Cheng
    Li, Rong-Shan
    Dong, Heng-Shan
    [J]. INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2009, 19 (01) : 99 - 100
  • [46] An Efficient Synthesis of 5-Aryl-4,5-dihydro-3-(5-methyl-1-ptolyl-1H-1,2,3-triazol-4-yl)-1-(4-phenylthiazol-2-yl)pyrazoles
    Dong, Wang-Jun
    Cui, Fu-Hong
    Gao, Zhong-Lian
    Li, Rong-Shan
    Shen, Guo-Liang
    Dong, Heng-Shan
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 48 (05) : 1154 - 1160
  • [47] 28-[1-(3-(Propionyloxy)propyl)-1H-1,2,3-triazol-4-yl]carbonylbetulin
    Kadela-Tomanek, Monika
    Chrobak, Elwira
    Bebenek, Ewa
    [J]. MOLBANK, 2022, 2022 (04)
  • [48] Synthesis and Structural Characterization of Isostructural 4-(4-Aryl)-2-(5-(4-fluorophenyl)-3-(1-(4-fluorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazoles
    Kariuki, Benson M.
    Abdel-Wahab, Bakr F.
    El-Hiti, Gamal A.
    [J]. CRYSTALS, 2021, 11 (07)
  • [49] Ethyl 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxylate
    Chen, Xiao-Bao
    Sun, Feng-Mei
    Xu, Jing
    Ma, Zuan
    Zheng, Ai-Hua
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O2402 - U2969
  • [50] Synthesis and Antimicrobial Evaluation of (1-(2-(Benzyloxy)-2-oxoethyl)-1H-1,2,3-triazol-4-yl)methyl Benzoate Analogues
    Kaushik, C. P.
    Pahwa, Ashima
    Kumar, Devinder
    Kumar, Ashwani
    Singh, Dharmendra
    Kumar, Krishan
    Luxmi, Raj
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (07) : 1720 - 1728