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Univ Toulouse, Ctr Hosp Univ Toulouse, Paule de Viguier Hosp, Dept Gynecol & Obstet,INSERM UMR 1048,I2MC, Toulouse, France Univ Toulouse, Ctr Hosp Univ Toulouse, Paule de Viguier Hosp, Dept Gynecol & Obstet,INSERM UMR 1048,I2MC, Toulouse, France