Optical measurement of blood flow changes in spinal cord injury

被引：1
|
作者：
Phillips, J. P. [1 ]
Kyriacou, P. A. [1 ]
George, K. J. [2 ]
Langford, R. M. [3 ]
机构：
[1] City Univ London, Biomed Engn Res Grp, London EC1V 0HB, England
[2] Queen Mary Univ London, Neurosci Ctr, London, England
[3] St Bartholomews Hospital, Pain & Anaesthesia Res Ctr, London, England
来源：
13TH IMEKO TC1-TC7 JOINT SYMPOSIUM - WITHOUT MEASUREMENT NO SCIENCE, WITHOUT SCIENCE NO MEASUREMENT | 2010年 / 238卷
关键词：
COMPRESSION; APOPTOSIS;
D O I：
10.1088/1742-6596/238/1/012060
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Little is known about cell death in spinal cord tissue following compression injury, despite compression being a key component of spinal injuries. Currently models are used to mimic compression injury in animals and the effects of the compression evaluated by observing the extent and duration of recovery of normal motor function in the days and weeks following the injury. A fibreoptic photoplethysmography system was used to investigate whether pulsation of the small arteries in the spinal cord occurred before, during and after compressive loads were applied to the tissue. It was found that the signal amplitudes were reduced and this reduction persisted for at least five minutes after the compression ceased. It is hoped that results from this preliminary study may improve knowledge of the mechanism of spinal cord injury.
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页数：5
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