Optical measurement of blood flow changes in spinal cord injury

被引：1
|
作者：
Phillips, J. P. [1 ]
Kyriacou, P. A. [1 ]
George, K. J. [2 ]
Langford, R. M. [3 ]
机构：
[1] City Univ London, Biomed Engn Res Grp, London EC1V 0HB, England
[2] Queen Mary Univ London, Neurosci Ctr, London, England
[3] St Bartholomews Hospital, Pain & Anaesthesia Res Ctr, London, England
来源：
13TH IMEKO TC1-TC7 JOINT SYMPOSIUM - WITHOUT MEASUREMENT NO SCIENCE, WITHOUT SCIENCE NO MEASUREMENT | 2010年 / 238卷
关键词：
COMPRESSION; APOPTOSIS;
D O I：
10.1088/1742-6596/238/1/012060
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Little is known about cell death in spinal cord tissue following compression injury, despite compression being a key component of spinal injuries. Currently models are used to mimic compression injury in animals and the effects of the compression evaluated by observing the extent and duration of recovery of normal motor function in the days and weeks following the injury. A fibreoptic photoplethysmography system was used to investigate whether pulsation of the small arteries in the spinal cord occurred before, during and after compressive loads were applied to the tissue. It was found that the signal amplitudes were reduced and this reduction persisted for at least five minutes after the compression ceased. It is hoped that results from this preliminary study may improve knowledge of the mechanism of spinal cord injury.
引用
收藏
页数：5
相关论文
共 50 条
  • [1] Intraoperative measurement of spinal cord blood flow in syringomyelia
    Young, WY
    Tuma, R
    O'Grady, T
    CLINICAL NEUROLOGY AND NEUROSURGERY, 2000, 102 (03) : 119 - 123
  • [2] Intraoperative Ultrasound to Monitor Spinal Cord Blood Flow after Spinal Cord Injury
    Manbachi, Amir
    Kambhampati, Sandeep
    Ainechi, Ana
    Mahapatra, Smruti
    Belzberg, Micah
    Ying, Guoliang
    Chai, Rongrong
    Zhang, Yu Shrike
    Gorelick, Noah
    Pennington, Zach
    Westbroek, Erick
    Jiang, Bowen
    Hwang, Brian
    Benassi, Thomas
    Coles, George
    Tyler, Betty
    Suk, Ian
    Yazdi, Youseph
    Theodore, Nicholas
    MEDICAL IMAGING 2020: BIOMEDICAL APPLICATIONS IN MOLECULAR, STRUCTURAL, AND FUNCTIONAL IMAGING, 2021, 11317
  • [3] Real-time direct measurement of spinal cord blood flow at the site of compression - Relationship between blood flow recovery and motor deficiency in spinal cord injury
    Hamamoto, Yuichiro
    Ogata, Tadanori
    Morino, Tadao
    Hino, Masayuki
    Yamamoto, Haruyasu
    SPINE, 2007, 32 (18) : 1955 - 1962
  • [4] Does passive cycling induce changes in peripheral blood flow in persons with spinal cord injury?
    Groothuis, Jan T.
    Hopman, Maria T.
    ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2007, 88 (12): : 1740 - 1740
  • [5] Measurement in spinal cord injury
    Edmond, P
    SPINAL CORD, 2004, 42 (04) : 209 - 210
  • [6] Measurement in spinal cord injury
    P Edmond
    Spinal Cord, 2004, 42 : 209 - 210
  • [7] Regulation of Cerebral Blood Flow after Spinal Cord Injury
    Phillips, Aaron A.
    Ainslie, Philip N.
    Krassioukov, Andrei V.
    Warburton, Darren E. R.
    JOURNAL OF NEUROTRAUMA, 2013, 30 (18) : 1551 - 1563
  • [8] Spinal cord blood flow measurement by arterial spin labeling
    Duhamel, Guillaume
    Callot, Virginie
    Cozzone, Patrick J.
    Kober, Frank
    MAGNETIC RESONANCE IN MEDICINE, 2008, 59 (04) : 846 - 854
  • [9] Spinal cord blood flow and pathophysiological changes after transient spinal cord ischemia in cats
    Yamada, T
    Morimoto, T
    Nakase, H
    Hirabayashi, H
    Hiramatsu, K
    Sakaki, T
    NEUROSURGERY, 1998, 42 (03) : 626 - 634
  • [10] The Effects of Spinal Cord Injury Induced by Shortening on Motor Evoked Potentials and Spinal Cord Blood Flow
    Modi, Hitesh N.
    Suh, Seung-Woo
    Hong, Jae-Young
    Yang, Jae-Hyuk
    JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2011, 93A (19): : 1781 - 1789
12345