Pauson-Khand reaction;
exo-cyclic enyne;
magellanine;
total synthesis;
D O I:
10.1016/S0040-4039(03)01516-8
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
Formal total synthesis of magellanine is described. Key features in the synthesis were stereoselective Ireland-Claisen rearrangement and intramolecular Pauson-Khand reaction of exo-cyclic enynes. (C) 2003 Elsevier Ltd. All rights reserved.
机构:
Mitsubishi Tanabe Pharma Co Ltd, Tianjin, Peoples R ChinaWaseda Univ, Grad Sch Adv Sci & Engn, Dept Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan
Utsugi, Masayuki
Iwamoto, Mitsuhiro
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机构:
Daiichi Sankyo Co Ltd, Tokyo, JapanWaseda Univ, Grad Sch Adv Sci & Engn, Dept Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan
Iwamoto, Mitsuhiro
Hirai, Sho
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机构:
Nippon Shinyaku Co Ltd, Kyoto, JapanWaseda Univ, Grad Sch Adv Sci & Engn, Dept Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan
Hirai, Sho
Kawada, Hatsuo
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机构:
Chugai Pharma Co Ltd, Tokyo, JapanWaseda Univ, Grad Sch Adv Sci & Engn, Dept Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan
Kawada, Hatsuo
Nakada, Masahisa
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机构:
Waseda Univ, Grad Sch Adv Sci & Engn, Dept Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, JapanWaseda Univ, Grad Sch Adv Sci & Engn, Dept Chem, Shinjuku Ku, 3-4-1 Ohkubo, Tokyo 1698555, Japan