The first total synthesis of (±)-laurokamurene B

被引:21
|
作者
Srikrishna, A. [1 ]
Khan, A. [1 ]
Babu, R. Ramesh [1 ]
Sajjanshetty, A. [1 ]
机构
[1] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India
关键词
D O I
10.1016/j.tet.2007.10.021
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The first total synthesis of the rearranged aromatic sesquiterpene (+/-)-laurokamurene B, isolated from the Chinese red alga Laurencia okamurai Yamada, has been accomplished, confirming the structure of the natural product. A combination of Ireland-Claisen rearrangement and ring-closing metathesis was employed as key reactions. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:12616 / 12620
页数:5
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