Noninvasive Test for Tuberculosis Detection among Primates

被引：11

作者：

Wolf, Tiffany M. ^{[1
,2
]}

Mugisha, Lawrence ^{[2
,3
,4
]}

Shoyama, Fernanda Miyagaki ^{[2
]}

O'Malley, Melanie J. ^{[5
]}

Flynn, JoAnne L. ^{[5
]}

Asiimwe, Benon ^{[4
]}

Travis, Dominic A. ^{[2
]}

Singer, Randall S. ^{[2
]}

Sreevatsan, Srinand ^{[2
]}

机构：

[1] Minnesota Zool Gardens, Apple Valley, MN USA

[2] Univ Minnesota, St Paul, MN 55108 USA

[3] Conservat & Ecosyst Hlth Alliance, Kampala, Uganda

[4] Makerere Univ, Kampala, Uganda

[5] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA

来源：

EMERGING INFECTIOUS DISEASES | 2015年 / 21卷 / 03期

关键词：

MYCOBACTERIUM-TUBERCULOSIS; PULMONARY TUBERCULOSIS;

D O I：

10.3201/eid2103.140052

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element 1S6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.

引用

页码：468 / 470

页数：3

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