Iron-catalysed radical cyclization to synthesize germanium-substituted indolo[2,1-a]isoquinolin-6(5H)-ones and indolin-2-ones

被引：49

作者：

Luo, Yani ^{[1
]}

Tian, Tian ^{[1
,2
]}

Nishihara, Yasushi ^{[2
]}

Lv, Leiyang ^{[1
]}

Li, Zhiping ^{[1
]}

机构：

[1] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China

[2] Okayama Univ, Res Inst Interdisciplinary Sci, Kita Ku, 3-1-1 Tsushimanaka, Okayama 7008530, Japan

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 73期

基金：

中国国家自然科学基金;

关键词：

ABSOLUTE RATE CONSTANTS; ACTIVATED ALKENES; HYDROGERMYLATION; SILICON; ALKYNES; ACCESS; TRIPHENYLGERMANE; ABILITIES; OXINDOLES; BOND;

D O I：

10.1039/d1cc03907e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple and efficient strategy for iron-catalysed cascade radical cyclization was developed, by which an array of germanium-substituted indolo[2,1-a]isoquinolin-6(5H)-ones and indolin-2-ones were obtained in one pot with germanium hydrides as radical precursors. A rapid intramolecular radical trapping mode enabled the selective arylgermylation of alkenes over the prevalent hydrogermylation reaction.

引用

页码：9276 / 9279

页数：4

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