Trans-synaptic plasticity: Presynaptic initiation, postsynaptic memory

被引:2
|
作者
Wan, Qin [1 ]
Abrams, Thomas W. [1 ,2 ,3 ]
机构
[1] Univ Maryland, Sch Med, Dept Pharmacol, Baltimore, MD 21201 USA
[2] Univ Maryland, Sch Med, Dept Anesthesiol, Baltimore, MD 21201 USA
[3] Univ Maryland, Sch Med, Program Neurosci, Baltimore, MD 21201 USA
关键词
D O I
10.1016/j.cub.2007.12.046
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A novel mechanism of persistent facilitation induced by serotonin at Aplysia synapses depends upon rapid postsynaptic protein synthesis and increased responsiveness to glutamate; whereas the memory for this synaptic change is postsynaptic, the initiating signal may be an increase in spontaneous release of glutamate from the presynaptic terminals.
引用
收藏
页码:R220 / R223
页数:4
相关论文
共 50 条
  • [1] Endostatin Is a Trans-Synaptic Signal for Homeostatic Synaptic Plasticity
    Wang, Tingting
    Hauswirth, Anna G.
    Tong, Amy
    Dickman, Dion K.
    Davis, Graeme W.
    NEURON, 2014, 83 (03) : 616 - 629
  • [2] Presynaptic Gating of Postsynaptic Synaptic Plasticity: A Plasticity Filter in the Adult Auditory Cortex
    Blundon, Jay A.
    Zakharenko, Stanislav S.
    NEUROSCIENTIST, 2013, 19 (05): : 465 - 478
  • [3] Presynaptic and Postsynaptic Mechanisms of Synaptic Plasticity and Metaplasticity during Intermediate-Term Memory Formation in Aplysia
    Antonov, Igor
    Kandel, Eric R.
    Hawkins, Robert D.
    JOURNAL OF NEUROSCIENCE, 2010, 30 (16): : 5781 - 5791
  • [4] Transsynaptic Coordination of Presynaptic and Postsynaptic Modifications underlying Enduring Synaptic Plasticity
    Ye, Xiaojing
    Carew, Thomas J.
    NEURON, 2011, 70 (03) : 379 - 381
  • [5] Acute knockdown of AMPA receptors reveals a trans-synaptic signal for presynaptic maturation
    Tracy, Tara E.
    Yan, Jenny J.
    Chen, Lu
    EMBO JOURNAL, 2011, 30 (08): : 1577 - 1592
  • [6] Synaptic Plasticity in Parkinson's Disease as Revealed by the Study of Trans-synaptic Cell Adhesion Molecules
    Hazrati, Lili-Naz
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2010, 69 (05): : 550 - 550
  • [7] TRANS-SYNAPTIC ENZYME-INDUCTION IN ADRENERGIC NEURONS AS A MODEL FOR NEURONAL PLASTICITY
    THOENEN, H
    OTTEN, U
    EXPERIMENTAL BRAIN RESEARCH, 1975, 23 : 197 - 197
  • [8] Synaptic plasticity and the postsynaptic density
    Nicoll, RA
    JOURNAL OF NEUROCHEMISTRY, 2003, 85 : 95 - 95
  • [9] TRANS-SYNAPTIC ATROPHY IN THE CEREBRAL CORTEX
    JONES, WH
    THOMAS, DB
    NATURE, 1956, 178 (4523) : 47 - 48
  • [10] Trans-synaptic assemblies link synaptic vesicles and neuroreceptors
    Martinez-Sanchez, Antonio
    Laugks, Ulrike
    Kochovski, Zdravko
    Papantoniou, Christos
    Zinzula, Luca
    Baumeister, Wolfgang
    Lucic, Vladan
    SCIENCE ADVANCES, 2021, 7 (10)