A review of hydrogel systems based on poly(N-isopropyl acrylamide) for use in the engineering of bone tissues

被引：18
|
作者：
Khiabani, Saeid Shabestari [1 ]
Aghazadeh, Marziyeh [2 ]
Rakhtshah, Jamshid [3 ]
Davaran, Soodabeh [4 ,5 ]
机构：
[1] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz, Iran
[2] Tabriz Univ Med Sci, Oral Med Dept, Dent Fac, Tabriz, Iran
[3] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz, Iran
[4] Tabriz Univ Med Sci, Fac Pharm, Tabriz, Iran
[5] Tabriz Univ Med Sci, Hlth Innovat Accelerat Ctr, Tabriz, Iran
来源：
COLLOIDS AND SURFACES B-BIOINTERFACES | 2021年 / 208卷
基金：
美国国家科学基金会;
关键词：
Hydrogel; Poly(N-isopropyl acrylamide); Tissue engineering; Crosslinking; Bone; BLOCK-COPOLYMER HYDROGELS; MESENCHYMAL STEM-CELLS; INJECTABLE HYDROGELS; HYALURONIC-ACID; DRUG-DELIVERY; CHITOSAN HYDROGELS; RELEASE; SCAFFOLDS; GEL; POLYMERS;
D O I：
10.1016/j.colsurfb.2021.112035
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Bone fracture is usually a medical condition where occurred by high force impact or stress. Recent advances to repair damaged or diseased bone tissues employs three-dimensional (3D) polymer matrices. This review aims to investigate the potential of injectable, dual thermally, and chemically gelable N-isopropyl acrylamide-based hydrogels to deliver scaffold, cells, and growth factors in vitro and in vivo.
引用
收藏
页数：9
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