Flexible Palladium-silver Nanowire Electrode for Non-enzymatic Glucose Detection

Diabetes has become a prominent issue that threatens human's health. Minimally invasive blood glucose testing may cause inconvenience and pain to patients. Wearable non-invasive blood glucose testing is becoming a hot topic in the scientific and medical field. In this study, novel palladium. silver nanowires (Pd. AgNWs) flexible electrodes were prepared by electrochemical deposition of Pd nanoparticles on the electrode with polydimethylsiloxane (PDMS) as the substrate and AgNWs as the conductive layer. The nanoparticles were uniformly deposited on AgNWs and different Pd. AgNWs electrodes were made by changing Pd deposition cycles. By using them as the working electrodes, glucose was detected by cyclic voltammetry. It was found that the Pd-AgNWs electrode deposited with 25 cycles of palladium had the best results in the detection of glucose. The experimental conditions of glucose detection were optimized. The linear ranges of glucose were 0.02-0.5 mmol/L and 1-4 mmol/L when detecting glucose by current.time method. The detection limit was 1 mu mol/L and the response sensitivity was 33.18 mu A/(cm(2)(mmol/L)) (S/N = 3). This electrode exhibited good reproducibility, stability, selectivity, as well as good response in detection of salivary glucose.