Nanotechnology for the management of COVID-19 during the pandemic and in the post-pandemic era

被引:10
|
作者
Xu, Chun [1 ,2 ]
Lei, Chang [3 ]
Hosseinpour, Sepanta [1 ,2 ]
Ivanovski, Saso [1 ,2 ]
Walsh, Laurence J. [1 ]
Khademhosseini, Ali [4 ]
机构
[1] Univ Queensland, Sch Dent, Brisbane, Qld 4006, Australia
[2] Univ Queensland, Sch Dent, Ctr Orofacial Regenerat Reconstruct & Rehabil COR, Brisbane, Qld 4006, Australia
[3] Univ Queensland, Australian Inst Bioengn & Nanotechnol, St Lucia, Qld 4072, Australia
[4] Terasaki Inst Biomed Innovat, Los Angeles, CA 90064 USA
基金
英国医学研究理事会;
关键词
COVID-19; nanotechnology; SARS-CoV-2; diagnosis; vaccines; MESSENGER-RNA VACCINE; NANOPARTICLES; DELIVERY; NANOMATERIALS; FORMULATIONS; RECOGNITION; LIPOSOMES; CHITOSAN; VIRUSES; SILVER;
D O I
10.1093/nsr/nwac124
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Following the global COVID-19 pandemic, nanotechnology has been at the forefront of research efforts and enables the fast development of diagnostic tools, vaccines and antiviral treatment for this novel virus (SARS-CoV-2). In this review, we first summarize nanotechnology with regard to the detection of SARS-CoV-2, including nanoparticle-based techniques such as rapid antigen testing, and nanopore-based sequencing and sensing techniques. Then we investigate nanotechnology as it applies to the development of COVID-19 vaccines and anti-SARS-CoV-2 nanomaterials. We also highlight nanotechnology for the post-pandemic era, by providing tools for the battle with SARS-CoV-2 variants and for enhancing the global distribution of vaccines. Nanotechnology not only contributes to the management of the ongoing COVID-19 pandemic but also provides platforms for the prevention, rapid diagnosis, vaccines and antiviral drugs of possible future virus outbreaks. This review highlights how nanotechnology helps us in the management of COVID-19 by providing detection methods, vaccines and antiviral treatments during the pandemic and in the post-pandemic era.
引用
收藏
页数:13
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