Non-traumatic rhabdomyolysis with gluteal ulcer

The case is presented of a 34-year-old woman with rhabdomyolysis due to massive intake of nimetazepam, a benzodiazepine hypnotic. On admission, the patient had numerous blisters all over the body One of the blisters in the gluteal region developed into a deep ulcer accompanied by muscle necrosis although it was not at a pressure point. The ulcer needed surgical intervention. Rhabdomyolysis is caused by the lysis and necrosis of muscle due to direct or indirect injury high fever, ischaemia, hypoxia or enzyme defects.(1-10) Release of myocyte components into the circulation then may induce major problems,(1-5) especially acute renal failure associated with hypermyoglobinaemia,(1,2,7-10) However, there have been few reports of cutaneous ulcer formation in non-traumatic rhabdomyolysis.(8,9).