For imaging purposes of the spine, segmented image data provide the basis of modem medical applications. Among them, finite element (FE) modelling for biomechanical analysis represents a promising tool in decision making and optimizing individual therapy in the future. Both the anatomical complex structure of the spine and the degenerative bony deformations apparent in the clinical situation complicate the application of fully automated segmentation and finite element modelling. We developed a software system that was specifically adapted to the spine anatomy, and enables a fast and accurate segmentation. That is provided by special adapted segmentation tools, taking the "axis"-skeletal structure of the spine into account (rotation transformation and warped dissection plane). Specifically bony parts with extensive degeneration can be presented with sufficient accuracy. The segmented data were further processed with a fully automatic FE model generation software. Compared to other automated model generators, the described system allows a more reliable representation of anatomical boarders without smoothing inaccuracies. The software was successfully applied to 30 cervical, thoracic and lumbar spines. Based on the present software environment, setup of multi-modal (CT- and MRI data-based) geometric models is a key of future investigation. (C) 2003 Elsevier Science B.V and CARS. All rights reserved.