Chemoselective palladium-catalyzed α-allylation of α-boryl aldehydes

被引：13
|
作者：
St Denis, Jeffrey D. [1 ]
He, Zhi [1 ]
Yudin, Andrei K. [1 ]
机构：
[1] Univ Toronto, Dept Chem, Davenport Res Labs, Toronto, ON M5H 3H5, Canada
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 39期
基金：
加拿大自然科学与工程研究理事会;
关键词：
CROSS-COUPLING REACTIONS; BORONIC ESTERS; ALDOL REACTION; ARYL; NUCLEOPHILES; ALKENYL;
D O I：
10.1039/c2ob26503f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Herein we report the development of an alpha-allylation reaction of alpha-boryl aldehydes that preserves the carbon-boron bond under Pd-0/Pd-II catalysis. Avariety of alpha-boryl aldehydes and allylic alcohols participate in this chemoselective transformation. The alpha-allylated products were obtained as single regioisomers.
引用
收藏
页码：7900 / 7902
页数：3
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