An efficient synthetic route to new imidazo[1,2-a]-pyridines by cross-coupling reactions in aqueous medium

被引：0
|
作者：
Castera, C [1 ]
Crozet, MD [1 ]
Vanelle, P [1 ]
机构：
[1] Univ Mediterranee, Fac Pharm, CNRS, UMR 6517,LCOP, F-13385 Marseille 5, France
来源：
HETEROCYCLES | 2005年 / 65卷 / 12期
关键词：
imidazo[1,2-a]pyridine; heteroaryl halide; sulfone; aryboronic acid; palladium;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Suzuki cross-coupling reaction of 6-bromo-3-nitro-2-phenylsulfonylmethylimidazo[ [1,2-a]pyridine and 6-bromo-3-nitro-2-tosylmethylimidazo[1,2-a]pyridine provided an efficient route to the corresponding 6-aryl3-nitro-2-phenylsulfonylmethylimidazo[ [1,2-a]pyridines and 6-aryl-3-nitro2-tosylmethylimidazo[ [1,2-a]pyridines. The reaction was catalyzed by palladium(0) in aqueous medium.
引用
收藏
页码：2979 / 2989
页数：11
相关论文
共 50 条
  • [1] An efficient microwave-assisted Suzuki cross-coupling reaction of imidazo[1,2-a]pyridines in aqueous medium
    Crozet, Maxime D.
    Castera-Ducros, Caroline
    Vanelle, Patrice
    TETRAHEDRON LETTERS, 2006, 47 (39) : 7061 - 7065
  • [2] Synthesis and Functionalization of Imidazo[1,2-a]Pyridines and Imidazo[1,2-a]Pyrimidines on Solid Phase Using Suzuki-Miyaura Cross-Coupling Reactions
    El Kazzouli, Said
    Berteina-Raboin, Sabine
    Mouaddib, Abderrahim
    Guillaumet, Gerald
    LETTERS IN ORGANIC CHEMISTRY, 2012, 9 (02) : 118 - 127
  • [3] Regioselective Copper-Catalyzed Oxidative Cross-Coupling of Imidazo[1,2-a] pyridines with Methyl Ketones: An Efficient Route for Synthesis of 1,2-Diketones
    Lei, Sai
    Chen, GuiJun
    Mai, Yingying
    Chen, Longbin
    Cai, Huiyin
    Tan, Jingwen
    Cao, Hua
    ADVANCED SYNTHESIS & CATALYSIS, 2016, 358 (01) : 67 - 73
  • [4] PREPARATION AND NEW REACTIONS OF IMIDAZO[1,2-A]PYRIDINES
    LOMBARDINO, JG
    JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (07): : 2403 - +
  • [5] Highly regioselective palladium-catalyzed direct cross-coupling of imidazo[1,2-a]pyridines with arylboronic acids
    Zhao, Limin
    Zhan, Haiying
    Liao, Jinqiang
    Huang, Jianping
    Chen, Qinlin
    Qiu, Huifang
    Cao, Hua
    CATALYSIS COMMUNICATIONS, 2014, 56 : 65 - 67
  • [6] An efficient synthesis of ferrocenyl imidazo[1,2-a]pyridines
    Roya Akbarzadeh
    Ghazaleh Imani Shakibaei
    Ayoob Bazgir
    Monatshefte für Chemie - Chemical Monthly, 2010, 141 : 1077 - 1081
  • [7] An efficient synthesis of ferrocenyl imidazo[1,2-a]pyridines
    Akbarzadeh, Roya
    Shakibaei, Ghazaleh Imani
    Bazgir, Ayoob
    MONATSHEFTE FUR CHEMIE, 2010, 141 (10): : 1077 - 1081
  • [8] New synthetic approaches to estrogen receptor modulators:: imidazo[1,2-a]pyridines
    Patel, HS
    Linn, JA
    Drewry, DH
    Hillesheim, DA
    Zuercher, WJ
    Hoekstra, WJ
    TETRAHEDRON LETTERS, 2003, 44 (21) : 4077 - 4080
  • [9] Magnetic Supported Copper Nanoparticles: An Efficient Heterogeneous Catalyst for the Synthesis of 1,2-Diketones by Cross-Coupling Reaction of Imidazo[1,2-a]pyridines with Methyl Ketones
    Liu, Yi
    Zhan, Haiying
    Yao, Kefan
    Mai, Yingying
    Wang, Enmin
    He, Juan
    Guo, Pengfeng
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 2016 (29) : 4991 - 4997
  • [10] Efficient synthesis of new polyfunctionalized thiadiazaacenaphthylenes from imidazo[1,2-a]pyridines
    Moreau, E
    Chezal, JM
    Dechambre, C
    Canitrot, D
    Blache, Y
    Lartigue, C
    Chavignon, O
    Teulade, JC
    HETEROCYCLES, 2002, 57 (01) : 21 - 38
12345