Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia and Neuroendocrine Hyperplasia of Infancy

被引：17
|
作者：
Carr, Laurie L. [1 ]
Kern, Jeffrey A. [1 ]
Deutsch, Gail H. [2 ]
机构：
[1] Natl Jewish Hlth, Div Oncol, 1400 Jackson St, Denver, CO 80206 USA
[2] Univ Washington, Dept Pathol, Seattle Childrens Hosp, 4800 Sand Point Way Northeast, Seattle, WA 98105 USA
来源：
CLINICS IN CHEST MEDICINE | 2016年 / 37卷 / 03期
关键词：
Diffuse idiopathic neuroendocrine cell hyperplasia; Neuroendocrine hyperplasia of infancy; Pulmonary neuroendocrine cells; PERSISTENT TACHYPNEA; FOLLOW-UP; LUNG; DISEASE; TUMORLETS; CHILDREN;
D O I：
10.1016/j.ccm.2016.04.018
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Although incidental reactive pulmonary neuroendocrine cell hyperplasia (PNECH) is seen on biopsy specimens in adults with chronic lung disease, disorders characterized by marked PNECH are rare. Primary hyperplasia of neuroendocrine cells in the lung and obstructive lung disease related to remodeling or physiologic constriction of small airways define diffuse idiopathic neuroendocrine cell hyperplasia (DIPENCH) in the adult and neuroendocrine cell hyperplasia of infancy (NEHI) in children. DIPENCH and NEHI share a similar physiology, typical imaging appearance, and increased neuroendocrine cells on biopsy. However, there are important differences related to the underlying disease mechanisms leading to disparate outcomes.
引用
收藏
页码：579 / +
页数：10
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