Toxic effect of Aβ25-35 and fullerene C60 on erythrocytes

被引:2
|
作者
Solomadin, I. N. [1 ]
Marov, N. V. [1 ]
Venediktova, N. I. [1 ]
Kosenko, E. A. [1 ]
Kaminsky, Yu. G. [1 ]
机构
[1] Russian Acad Sci, Inst Theoret & Expt Biophys, Pushchino 142290, Moscow Region, Russia
关键词
D O I
10.1134/S1062359008040171
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Using light microscopy and spectrophotometry, it has been shown that amyloid beta-peptide A beta(25-35) and water-soluble fullerene C-60 cause lysis of human and rat erythrocytes. Both fullerene C-60 and A beta(25-35) partly inhibited the activities of membrane-associated phosphofructokinase and cytoplasmic lactate dehydrogenase in erythrocytes.
引用
收藏
页码:436 / 440
页数:5
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