Onchocerciasis dynamics: modelling the effects of treatment, education and vector control

被引:7
|
作者
Hassan, Asha [1 ]
Shaban, Nyimvua [1 ]
机构
[1] Univ Dar Es Salaam, Dept Math, Dar Es Salaam, Tanzania
关键词
Onchocerciasis; ivermectin; public health education; larviciding; trapping; EPIDEMIOLOGIC MODELS; CONTROL PROGRAM; IVERMECTIN; DISEASE; TRANSMISSION; INFECTION; VOLVULUS;
D O I
10.1080/17513758.2020.1745306
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071012 ; 0713 ;
摘要
A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ivermectin drugs. Also, larviciding and trapping strategies are implemented in the vector population with the aim of controlling population growth of black flies. We fit the model to the data to check the suitability of the model. Expressions are derived for the influence on the reproduction numbers of these strategies. Numerical results show that the dynamics of onchocerciasis and the growth of black flies are best controlled when the four strategies are implemented simultaneously. Also, the results suggest that for the elimination of the disease in the society there is a need for finding another drug which will be implemented to ineligible human as well as killing the adult worms instead of ivermectin.
引用
收藏
页码:245 / 268
页数:24
相关论文
共 50 条
  • [41] How Can Onchocerciasis Elimination in Africa Be Accelerated? Modeling the Impact of Increased Ivermectin Treatment Frequency and Complementary Vector Control
    Verver, Suzanne
    Walker, Martin
    Kim, Young Eun
    Fobi, Grace
    Tekle, Afework H.
    Zoure, Honorat G. M.
    Wanji, Samuel
    Boakye, Daniel A.
    Kuesel, Annette C.
    de Vlas, Sake J.
    Boussinesq, Michel
    Basanez, Maria-Gloria
    Stolk, Wilma A.
    CLINICAL INFECTIOUS DISEASES, 2018, 66 : S267 - S274
  • [42] ONCHOCERCIASIS: SHIFT FROM CONTROL TO ELIMINATION-VECTOR CONTROL SHALL NOT REMAIN UNDER A BUSHEL!
    Katabarwa, Moses N.
    Richards, Frank
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2015, 93 (04): : 136 - 136
  • [43] Reduced prevalence of onchocerciasis in Uganda following either deforestation or vector control with DDT
    Fischer, P
    Garms, R
    Buttner, DW
    Kipp, W
    Bamuhiiga, J
    Yocha, J
    EAST AFRICAN MEDICAL JOURNAL, 1997, 74 (05) : 321 - 325
  • [44] Validation Steps For Vector Control Modelling
    Oprea, Andrei
    Floricau, Dan
    Kisck, Dragos Ovidiu
    2021 INTERNATIONAL CONFERENCE ON APPLIED AND THEORETICAL ELECTRICITY (ICATE), 2021,
  • [45] Learning and control by Vector Field modelling
    Cook, PA
    Hayden, JV
    UKACC INTERNATIONAL CONFERENCE ON CONTROL '98, VOLS I&II, 1998, : 775 - 780
  • [46] Modelling and Optimal Control of Influenza Dynamics with Structured Populations Based on Education and Isolation
    Olaniyi, Samson
    Lawal, Idris A.
    Lebelo, Ramoshweu S.
    Chuma, Furaha M.
    Abimbade, Sulaimon F.
    INTERNATIONAL JOURNAL OF ANALYSIS AND APPLICATIONS, 2025, 23
  • [47] Transmission dynamics of onchocerciasis with two classes of infection and saturated treatment function
    Idowu, Amos Sesan
    Ogunmiloro, Oluwatayo Michael
    INTERNATIONAL JOURNAL OF MODELING SIMULATION AND SCIENTIFIC COMPUTING, 2020, 11 (05)
  • [48] Modelling and control of HIV dynamics
    Landi, Alberto
    Mazzoldi, Alberto
    Andreoni, Chiara
    Bianchi, Matteo
    Cauallini, Andrea
    Laurino, Marco
    Ricotti, Leonardo
    Luliano, Rodolfio
    Matteoli, Barbara
    Ceccherini-Nelli, Luca
    COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2008, 89 (02) : 162 - 168
  • [49] IRREVERSIBLE EFFECTS OF IVERMECTIN ON ADULT PARASITES IN ONCHOCERCIASIS PATIENTS IN THE ONCHOCERCIASIS CONTROL PROGRAM IN WEST-AFRICA
    PLAISIER, AP
    ALLEY, ES
    BOATIN, BA
    VANOORTMARSSEN, GJ
    REMME, H
    DEVLAS, SJ
    BONNEUX, L
    HABBEMA, JDF
    JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (01): : 204 - 210
  • [50] A 3-YEAR FOLLOW-UP OF OCULAR ONCHOCERCIASIS IN AN AREA OF VECTOR CONTROL
    THYLEFORS, B
    TONJUM, AM
    BULLETIN OF THE WORLD HEALTH ORGANIZATION, 1980, 58 (01): : 107 - 112