Extract from leaves of Nelumbo nucifera was obtained and studies were conducted to observe its hypoglycemic activity. The drug extracts were found to be safe at 4gm/kg body weight. The work was conducted in normal and alloxan induced diabetic rats using alcoholic extract of Nelumbo nucifera leaf. The alcoholic extract of Nelumbo nucifera leaf was found to produce hypoglycemic effect-in both single and chronic dose administration, in normal as well as diabetic rats. It was inferred that the leaf extract of Nelumbo nucifera possess hypoglycemic activity similar to that observed with the hypoglycemic drug Glibenclamide.
机构:Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan
Ono, Yuka
Hattori, Eri
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机构:Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan
Hattori, Eri
Fukaya, Yukitaka
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机构:Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan
Fukaya, Yukitaka
Imai, Shoji
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机构:Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan
Imai, Shoji
Ohizumi, Yasushi
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Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, JapanTohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan