Upper Urinary Tract Infections Are Associated with RANTES Promoter Polymorphism

被引：10
|
作者：
Centi, Sonia [1 ]
Negrisolo, Susanna [1 ]
Stefanic, Alejandra [1 ]
Benetti, Elisa [2 ]
Cassar, Walburga [3 ]
Da Dalt, Liviana
Rigamonti, Waifro [4 ]
Zucchetta, Pietro [5 ]
Montini, Giovanni [6 ]
Murer, Luisa [2 ]
Artifoni, Lina [1 ]
机构：
[1] Univ Padua, Dept Pediat Salus Pueri, Lab Immunopathol & Mol Biol Kidney, I-35128 Padua, Italy
[2] Univ Padua, Dept Pediat Salus Pueri, Dialysis & Transplant Unit, I-35128 Padua, Italy
[3] Hosp Bolzano, Pediat Unit, Bolzano, Italy
[4] Univ Padua, Inst Urol, Urol Unit, I-35128 Padua, Italy
[5] Univ Padua, Nucl Med Serv, I-35128 Padua, Italy
[6] Azienda Osped Univ St Orsola, Nephrol & Dialysis Unit, Dept Pediat, Bologna, Italy
来源：
JOURNAL OF PEDIATRICS | 2010年 / 157卷 / 06期
关键词：
TRANSCRIPTIONAL REGULATION; HIV-1; INFECTION; GENE; CHEMOKINES; EXPRESSION; VARIANTS; DISEASE;
D O I：
10.1016/j.jpeds.2010.08.006
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
We evaluated the association between MCP-1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES-403 G>A genotype frequencies showed that children carrying the RANTES-403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux. (J Pediatr 2010;157:1038-40)
引用
收藏
页码：1038 / U238
页数：4
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