Upper Urinary Tract Infections Are Associated with RANTES Promoter Polymorphism

被引：10

作者：

Centi, Sonia ^{[1
]}

Negrisolo, Susanna ^{[1
]}

Stefanic, Alejandra ^{[1
]}

Benetti, Elisa ^{[2
]}

Cassar, Walburga ^{[3
]}

Da Dalt, Liviana

Rigamonti, Waifro ^{[4
]}

Zucchetta, Pietro ^{[5
]}

Montini, Giovanni ^{[6
]}

Murer, Luisa ^{[2
]}

Artifoni, Lina ^{[1
]}

机构：

[1] Univ Padua, Dept Pediat Salus Pueri, Lab Immunopathol & Mol Biol Kidney, I-35128 Padua, Italy

[2] Univ Padua, Dept Pediat Salus Pueri, Dialysis & Transplant Unit, I-35128 Padua, Italy

[3] Hosp Bolzano, Pediat Unit, Bolzano, Italy

[4] Univ Padua, Inst Urol, Urol Unit, I-35128 Padua, Italy

[5] Univ Padua, Nucl Med Serv, I-35128 Padua, Italy

[6] Azienda Osped Univ St Orsola, Nephrol & Dialysis Unit, Dept Pediat, Bologna, Italy

来源：

JOURNAL OF PEDIATRICS | 2010年 / 157卷 / 06期

关键词：

TRANSCRIPTIONAL REGULATION; HIV-1; INFECTION; GENE; CHEMOKINES; EXPRESSION; VARIANTS; DISEASE;

D O I：

10.1016/j.jpeds.2010.08.006

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We evaluated the association between MCP-1, CCR2, RANTES, and CCR5 gene polymorphisms and upper urinary tract infection in 273 children recruited in Northeast Italy. Statistical analysis of RANTES-403 G>A genotype frequencies showed that children carrying the RANTES-403 G allele are at higher risk for urinary tract infection, irrespective of vesicoureteral reflux. (J Pediatr 2010;157:1038-40)

引用

页码：1038 / U238

页数：4

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