A cascade of thromboembolic processes in a patient with paroxysmal nocturnal haemoglobinuria terminated by treatment with eculizumab

被引:5
|
作者
Schutgens, Roger E. G. [1 ]
Pruissen-Peeters, Kim A. B. M. [2 ]
Muus, Petra [3 ]
机构
[1] Univ Med Ctr Utrecht, Dept Hematol Van Creveldklin, NL-3584 CX Utrecht, Netherlands
[2] Univ Med Ctr Utrecht, Dept Dermatol Allergol, NL-3584 CX Utrecht, Netherlands
[3] Univ Nijmegen Hosp, Dept Hematol, Nijmegen, Netherlands
关键词
COMPLEMENT INHIBITOR ECULIZUMAB; PLASMINOGEN-ACTIVATOR RECEPTOR; NATURAL-HISTORY; THROMBOSIS; PLATELETS; PNH; INFECTION;
D O I
10.1160/TH11-03-0165
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:383 / 385
页数:3
相关论文
共 50 条
  • [21] Eculizumab for paroxysmal nocturnal haemoglobinuria: catastrophic health expenditure in Nepalese patients
    Adhikari, Sugat
    Sapkota, Surendra
    Shrestha, Suraj
    Karki, Kshitiz
    Shrestha, Anjan
    ORPHANET JOURNAL OF RARE DISEASES, 2023, 18 (01)
  • [22] Pregnancy outcomes in women receiving eculizumab for the management of paroxysmal nocturnal haemoglobinuria
    Anderson, Rachel
    Manning, James
    Hill, Anita
    Ciantar, Etienne
    BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2024, 132 : 33 - 33
  • [23] SUCCESSFUL PREGNANCY OUTCOME IN PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA ON LONG TERM ECULIZUMAB
    Kelly, R.
    Arnold, L. M.
    Richards, S. J.
    Hill, A.
    Bomken, C.
    Hanley, J.
    Loughney, A.
    Beauchamp, J.
    Khursigara, G.
    Rother, R. P.
    Chalmers, E.
    Gartnavel, A. Fyfe
    Fitzsimons, E.
    Nakamura, R.
    Gaya, A.
    Rotoli, B.
    Risitano, A.
    Schubert, J.
    Hillmen, P.
    HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 452 - 452
  • [24] Eculizumab for paroxysmal nocturnal haemoglobinuria: catastrophic health expenditure in Nepalese patients
    Sugat Adhikari
    Surendra Sapkota
    Suraj Shrestha
    Kshitiz Karki
    Anjan Shrestha
    Orphanet Journal of Rare Diseases, 18
  • [25] ASSESSMENT OF FERRIC OVERLOAD IN PATIENTS WITH PAROXYSMAL NOCTURNAL HAEMOGLOBINURIA TREATED WITH ECULIZUMAB
    Eduardo Jose, Salido Fierrez
    Piqueras Mercedes, Berenguer
    Perianes Valentin, Cabanas
    Raul, Perez-Lopez
    Faustino, Garcia-Candel
    Juan Jose, Cerezo Manchado
    Ana Maria, Garcia-Hernandez
    Amor Antonia, Melero
    Arnao Maria, Moya
    Marin Amelia, Martinez
    Poveda Elena, Fernandez
    Almenzar Begona, Navarro
    Jose Maria, Moraleda Jimenez
    HAEMATOLOGICA, 2016, 101 : 263 - 264
  • [26] Fibrinogen and Clot Structure Is Affected By Eculizumab in Patients with Paroxysmal Nocturnal Haemoglobinuria
    Macrae, Fraser
    Bowman, Polly
    Linton, Emma
    Peacock-Young, Barnaby
    Clarke, Deborah
    Newton, Darren J.
    McKinley, Claire E.
    Riley, Kathryn
    Copeland, Nicola
    Arnold, Louise
    Griffin, Morag
    Munir, Talha
    Hillmen, Peter
    Richards, Stephen John
    Ariens, Robert
    Hill, Anita
    BLOOD, 2017, 130
  • [27] Pregnancy outcomes in women receiving eculizumab for the management of paroxysmal nocturnal haemoglobinuria
    Manning, James E.
    Anderson, Rachel M.
    Hill, Anita
    Zeidan, Doaa
    Ciantar, Etienne
    OBSTETRIC MEDICINE, 2022, 15 (01) : 45 - 49
  • [28] Long term treatment with eculizumab in paroxysmal nocturnal haemoglobinuria (PNH): sustained efficacy and improved survival
    Kelly, R. J.
    Hill, A.
    Arnold, L. M.
    Brooksbank, G. L.
    Richards, S. J.
    Cullen, M.
    Mitchell, L. D.
    Cohen, D. R.
    Gregory, W. M.
    Hillmen, P.
    BRITISH JOURNAL OF HAEMATOLOGY, 2011, 153 : 26 - 26
  • [29] Purpura fulminans in a patient with paroxysmal nocturnal haemoglobinuria
    May, C.
    O'Rourke, K.
    Jackson, K.
    Francis, L.
    Kennedy, G. A.
    INTERNAL MEDICINE JOURNAL, 2013, 43 (01) : 102 - 102
  • [30] Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria
    Hillmen, Peter
    Muus, Petra
    Roeth, Alexander
    Elebute, Modupe O.
    Risitano, Antonio M.
    Schrezenmeier, Hubert
    Szer, Jeffrey
    Browne, Paul
    Maciejewski, Jaroslaw P.
    Schubert, Joerg
    Urbano-Ispizua, Alvaro
    de Castro, Carlos
    Socie, Gerard
    Brodsky, Robert A.
    BRITISH JOURNAL OF HAEMATOLOGY, 2013, 162 (01) : 62 - 73