Gene expression and protein abundance of clinically relevant phase I & II enzymes in the human intestine

被引：0
|
作者：
Busch, D. [1 ]
Drozdzik, M. [2 ]
Siegmund, W. [1 ]
Oswald, S. [1 ]
机构：
[1] Univ Med Greifswald, Clin Pharmacol, Greifswald, Germany
[2] Pomeranian Med Univ, Dept Expt & Clin Pharmacol, Szczecin, Poland
来源：
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY | 2015年 / 388卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
244
引用
收藏
页码：S62 / S62
页数：1
相关论文
共 50 条
  • [21] Expression of clinically relevant drug-metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra-subject analysis
    Fritz, Anja
    Busch, Diana
    Lapczuk, Joanna
    Ostrowski, Marek
    Drozdzik, Marek
    Oswald, Stefan
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 124 (03) : 245 - 255
  • [22] Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine
    Bruckmueller, Henrike
    Martin, Paul
    Kaehler, Meike
    Haenisch, Sierk
    Ostrowski, Marek
    Drozdzik, Marek
    Siegmund, Werner
    Cascorbite, Ingolf
    Oswaldii, Stefan
    MOLECULAR PHARMACEUTICS, 2017, 14 (07) : 2245 - 2253
  • [23] Regulation of gene expression of various phase I and phase II drug-metabolizing enzymes by tamoxifen in rat liver
    Hellriegel, ET
    Matwyshyn, GA
    Fei, PW
    Dragnev, KH
    Nims, RW
    Lubet, RA
    Kong, ANT
    BIOCHEMICAL PHARMACOLOGY, 1996, 52 (10) : 1561 - 1568
  • [24] Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human Preeclampsia
    Leavey, Katherine
    Benton, Samantha J.
    Grynspan, David
    Kingdom, John C.
    Bainbridge, Shannon A.
    Cox, Brian J.
    HYPERTENSION, 2016, 68 (01) : 137 - +
  • [25] Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors
    Spivack, SD
    Hurteau, GJ
    Fasco, MJ
    Kaminsky, LS
    CLINICAL CANCER RESEARCH, 2003, 9 (16) : 6002 - 6011
  • [26] Characteristics of biotransformation phase I and phase II enzymes in human fetal adrenals
    Wang, Hui
    Ping, Jie
    Peng, Ren-Xiu
    Lr, Jiang
    DRUG METABOLISM REVIEWS, 2006, 38 : 42 - 42
  • [27] Gene Expression of Metabolizing Enzymes in Beagle Dog Intestine
    Park, Sung-Won
    Yi, Hee
    Cho, Soo-Min
    Jo, Kyul
    Park, Jin-A
    Shin, Soo-Jean
    Cho, Hee-Jung
    Song, Si-Whan
    Jeong, Sang Min
    Shin, Ho-Chul
    JOURNAL OF ANIMAL AND VETERINARY ADVANCES, 2011, 10 (15): : 1947 - 1955
  • [28] Regional Proteomic Quantification of Clinically Relevant Non-Cytochrome P450 Enzymes along the Human Small Intestine
    Zhang, Haeyoung
    Wolford, Chris
    Basit, Abdul
    Li, Albert P.
    Fan, Peter W.
    Murray, Bernard P.
    Takahashi, Ryan H.
    Khojasteh, S. Cyrus
    Smith, Bill J.
    Thummel, Kenneth E.
    Prasad, Bhagwat
    DRUG METABOLISM AND DISPOSITION, 2020, 48 (07) : 528 - 536
  • [29] Gene expression of phase I and phase II metabolizing enzymes and PAH-DNA adduct formation in human prostate as risk factors in prostate cancer etiology
    John, K.
    Singh, P. B.
    Pratt, M. M.
    Ragavan, N.
    Cole, K. C.
    Matanhelia, S. S.
    Phillips, D. H.
    Martin, F. L.
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2008, 49 (07) : 557 - 557
  • [30] CLINICALLY RELEVANT MULTIDRUG TRANSPORTERS ARE REGULATED BY DIFFERENT MICRORNAS ALONG THE HUMAN INTESTINE
    Bruckmueller, H.
    Martin, P.
    Kaehler, M.
    Haenisch, S.
    Ostrowski, M.
    Drozdzik, M.
    Siegmund, W.
    Oswald, S.
    Cascorbi, I.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2017, 101 (S1) : S98 - S98
12345