Hydrogen sulfide-activatable fluorescence turn-on azide-containing naphthalimide derivative

被引:8
|
作者
Yoo, Song Yi [1 ]
Gopala, Lavanya [1 ]
Kang, Chulhun [2 ]
Lee, Min Hee [1 ]
机构
[1] Sookmyung Womens Univ, Dept Chem, Seoul 04310, South Korea
[2] Kyung Hee Univ, Sch East West Med Sci, Yongin 17104, South Korea
基金
新加坡国家研究基金会;
关键词
azide-containing naphthalimide; fluorescent turn-on probe; hydrogen sulfide; intramolecular charge transfer;
D O I
10.1002/bkcs.12611
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Hydrogen sulfide (H2S) acts as a crucial biological and environmental component in a variety of processes. Abnormal levels of H2S endogenously generated in human body are associated with various diseases. Meanwhile, H2S gas leaked from various manufacturing environments has a fatal effect against the human body. For this reason, H2S has been considered as a potential biomarker for the diagnosis and treatment of various human diseases, and as a toxic gas that should be detected when leaked to the workplace for the safety of workers. In this study, we synthesized an azide-containing naphthalimide derivative that can play as a fluorescence turn-on probe for H2S.
引用
收藏
页码:1231 / 1235
页数:5
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