An ESIPT based fluorescent probe for imaging hydrogen sulfide with a large turn-on fluorescence signal

被引：20
|
作者：
Deng, Beibei [1 ]
Ren, Mingguang [1 ]
Kong, Xiuqi [1 ]
Zhou, Kai [1 ]
Lin, Weiying [1 ]
机构：
[1] Univ Jinan, Sch Biol Sci & Technol, Sch Chem & Chem Engn, Inst Fluorescent Probes Biol Imaging, Jinan 250022, Shandong, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 67期
关键词：
H2S; EMISSION; CHEMODOSIMETER; DYE;
D O I：
10.1039/c6ra12127f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Through an intramolecular nucleophilic substitution reaction and ESIPT mechanism, we designed and synthesized a fluorescent hydrogen sulfide probe with a large turn on fluorescence signal (400-fold). The new probe exhibits high selectivity, good membrane-permeability and is suitable for the visualization of exogenous and endogenous hydrogen sulfide in living cells.
引用
收藏
页码：62406 / 62410
页数：5
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