Fixed-parameter algorithms in phylogenetics

被引:17
|
作者
Gramm, Jens [2 ]
Nickelsen, Arfst [1 ]
Tantau, Till [1 ]
机构
[1] Med Univ Lubeck, Inst Theoret Informat, Lubeck, Germany
[2] Univ Tubingen, Wilhelm Schickard Inst Informat, D-72074 Tubingen, Germany
来源
COMPUTER JOURNAL | 2008年 / 51卷 / 01期
关键词
bioinformatics; phylogenetics algorithms; parameterized algorithms;
D O I
10.1093/comjnl/bxm049
中图分类号
TP3 [计算技术、计算机技术];
学科分类号
0812 ;
摘要
We survey the use of fixed-parameter algorithms in the field of phylogenetics, which is the study of evolutionary relationships. The central problem in phylogenetics is the reconstruction of the evolutionary history of biological species, but its methods also apply to linguistics, philology or architecture. A basic computational problem is the reconstruction of a likely phylogeny ( genealogical tree) for a set of species based on observed differences in the phenotype like color or form of limbs, based on differences in the genotype like mutated nucleotide positions in the DNA sequence, or based on given partial phylogenies. Ideally, one would like to construct socalled perfect phylogenies, which arise from a very simple evolutionary model, but in practice one must often be content with phylogenies whose 'distance from perfection' is as small as possible. The computation of phylogenies has applications in seemingly unrelated areas such as genomic sequencing and finding and understanding genes. The numerous computational problems arising in phylogenetics often are NP-complete, but for many natural parametrizations they can be solved using fixed-parameter algorithms.
引用
收藏
页码:79 / 101
页数:23
相关论文
共 50 条
  • [11] Fixed-Parameter Algorithms for Closed World Reasoning
    Lackner, Martin
    Pfandler, Andreas
    20TH EUROPEAN CONFERENCE ON ARTIFICIAL INTELLIGENCE (ECAI 2012), 2012, 242 : 492 - 497
  • [12] FIXED-PARAMETER ALGORITHMS FOR THE KNESER AND SCHRIJVER PROBLEMS
    Haviv, Ishay
    SIAM JOURNAL ON COMPUTING, 2024, 53 (02) : 287 - 314
  • [13] Fixed-Parameter Algorithms for Unsplittable Flow Cover
    Cristi, Andres
    Mari, Mathieu
    Wiese, Andreas
    THEORY OF COMPUTING SYSTEMS, 2023, 67 (01) : 89 - 124
  • [14] Fixed-Parameter Algorithms for Unsplittable Flow Cover
    Andrés Cristi
    Mathieu Mari
    Andreas Wiese
    Theory of Computing Systems, 2023, 67 : 89 - 124
  • [15] FIXED-PARAMETER ALGORITHMS FOR FINDING AGREEMENT SUPERTREES
    Fernandez-Baca, David
    Guillemot, Sylvain
    Shutters, Brad
    Vakati, Sudheer
    SIAM JOURNAL ON COMPUTING, 2015, 44 (02) : 384 - 410
  • [16] Two Fixed-Parameter Algorithms for the Cocoloring Problem
    Campos, Victor
    Klein, Sulamita
    Sampaio, Rudini
    Silva, Ana
    ALGORITHMS AND COMPUTATION, 2011, 7074 : 634 - +
  • [17] Fixed-Parameter Algorithms for Cluster Vertex Deletion
    Hueffner, Falk
    Komusiewicz, Christian
    Moser, Hannes
    Niedermeier, Rolf
    THEORY OF COMPUTING SYSTEMS, 2010, 47 (01) : 196 - 217
  • [18] Ubiquitous parameterization - Invitation to fixed-parameter algorithms
    Niedermeier, R
    MATHEMATICAL FOUNDATIONS OF COMPUTER SCIENCE 2004, PROCEEDINGS, 2004, 3153 : 84 - 103
  • [19] Fixed-parameter algorithms for cluster vertex deletion
    Hueffner, Falk
    Komusiewicz, Christian
    Moser, Hannes
    Niedermeier, Rolf
    LATIN 2008: THEORETICAL INFORMATICS, 2008, 4957 : 711 - 722
  • [20] Fixed-Parameter Algorithms for Unsplittable Flow Cover
    Cristi, Andres
    Mari, Mathieu
    Wiese, Andreas
    37TH INTERNATIONAL SYMPOSIUM ON THEORETICAL ASPECTS OF COMPUTER SCIENCE (STACS 2020), 2020, 154