The SPECTRA Study: A Phase 2a Single-Arm, Open-Label, Multicenter Exploratory Study to Assess the Effects of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH)

被引:0
|
作者
Waxman, A. B. [1 ]
Risbano, M. G. [2 ]
Frantz, R. P. [3 ]
Manimaran, S. [4 ]
Lu, J. [4 ]
Rischard, F. [5 ]
机构
[1] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[2] Univ Pittsburgh, Pittsburgh, PA USA
[3] Mayo Clin, Rochester, NY USA
[4] Acceleron Pharma, Cambridge, MA USA
[5] Univ Arizona, Tucson, AZ USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A1187
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Safety and efficacy of azilsartan in paediatric patients with hypertension: a phase 3, single-arm, open-label, prospective study
    Shuichi Ito
    Yuya Nishiyama
    Kenkichi Sugiura
    Kazuaki Enya
    [J]. Clinical and Experimental Nephrology, 2022, 26 : 350 - 358
  • [22] Open-label, single-arm, phase II study of enzastaurin in patients with follicular lymphoma
    Schwartzberg, Lee
    Hermann, Robert
    Flinn, Ian
    Flora, Douglas
    Hsi, Eric D.
    Hamid, Oday
    Shi, Peipei
    Lin, Boris K.
    Myrand, Scott P.
    Nguyen, Tuan S.
    Dreyling, Martin
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2014, 166 (01) : 91 - 97
  • [23] Vardenafil treatment for patients with pulmonary arterial hypertension: a multicentre, open-label study
    Jing, Z-C
    Jiang, X.
    Wu, B-X
    Xu, X-Q
    Wu, Y.
    Ma, C-R
    Wang, Y.
    Yang, Y-J
    Pu, J-L
    Gao, W.
    [J]. HEART, 2009, 95 (18) : 1531 - 1536
  • [24] Pazopanib for the Treatment of Non-clear Cell Renal Cell Carcinoma: A Single-Arm, Open-Label, Multicenter, Phase II Study
    Jung, Ki Sun
    Lee, Su Jin
    Park, Se Hoon
    Lee, Jae-Lyun
    Lee, Se-Hoon
    Lim, Jae Yun
    Kang, Jung Hun
    Lee, Suee
    Rha, Sun Young
    Lee, Kyung Hee
    Kim, Ho Young
    Lim, Ho Yeong
    [J]. CANCER RESEARCH AND TREATMENT, 2018, 50 (02): : 488 - 494
  • [25] IL-1 Blockade Reduces Inflammation in Pulmonary Arterial Hypertension and Right Ventricular Failure: A Single-Arm, Open-Label, Phase IB/II Pilot Study
    Trankle, Cory R.
    Canada, Justin M.
    Kadariya, Dinesh
    Markley, Roshanak
    De Chazal, Horacio Medina
    Pinson, Janet
    Fox, Adam
    Van Tassell, Benjamin W.
    Abbate, Antonio
    Grinnan, Daniel
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199 (03) : 381 - 384
  • [26] Apremilast for Discoid Lupus Erythematosus: Results of a Phase 2, Open-Label, Single-Arm, Pilot Study
    De Souza, Aieska
    Strober, Bruce E.
    Merola, Joseph F.
    Oliver, Stephen
    Franks, Andrew G., Jr.
    [J]. JOURNAL OF DRUGS IN DERMATOLOGY, 2012, 11 (10) : 1224 - 1226
  • [27] A phase 3b, multicenter, open-label, single-arm study of roxadustat within a US dialysis organization: The DENALI study
    Larkin, John
    Hymes, Jeffrey
    Britton, Marcus L.
    Oluwatosin, Yemmie
    Nolen, Jacqueline
    Zhu, Lixia
    Silva, Arnold
    [J]. HEMODIALYSIS INTERNATIONAL, 2024, 28 (01) : 59 - 71
  • [28] Long-term safety of nebivolol and valsartan combination therapy in patients with hypertension: an open-label, single-arm, multicenter study
    Neutel, Joel M.
    Giles, Thomas D.
    Punzi, Henry
    Weiss, Robert J.
    Li, Huiling
    Finck, Amy
    [J]. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2014, 8 (12) : 915 - 920
  • [29] Evaluation of orelabrutinib monotherapy in patients with relapsed or refractory Waldenstrom's macroglobulinemia in a single-arm, multicenter, open-label, phase 2 study
    Cao, Xin-Xin
    Jin, Jie
    Fu, Cheng-Cheng
    Yi, Shu-Hua
    Zhao, Wei-Li
    Sun, Zi-Min
    Yang, Wei
    Li, Deng-Ju
    Cui, Guo-Hui
    Hu, Jian-da
    Liu, Ting
    Song, Yong-Ping
    Xu, Bing
    Zhu, Zun-Min
    Xu, Wei
    Zhang, Ming-Zhi
    Tian, Ya-Min
    Zhang, Bin
    Zhao, Ren-Bin
    Zhou, Dao-Bin
    [J]. ECLINICALMEDICINE, 2022, 52
  • [30] A multicenter, open-label, uncontrolled, single-arm phase 2 study of tirabrutinib, an oral Bruton's tyrosine kinase inhibitor, in pemphigus
    Yamagami, Jun
    Ujiie, Hideyuki
    Aoyama, Yumi
    Ishii, Norito
    Tateishi, Chiharu
    Ishiko, Akira
    Ichijima, Tomoki
    Hagihara, Shunsuke
    Hashimoto, Koji
    Amagai, Masayuki
    [J]. JOURNAL OF DERMATOLOGICAL SCIENCE, 2021, 103 (03) : 135 - 142