Idiopathic hypereosinophilic syndrome involving the middle ear: Clinical case report and discussion

Multiple organ system involvement is seen in the idiopathic hypereosinophilic syndrome (HES). Cardiovascular, lung and upper airway, liver, spleen, skin and nervous systems are frequently involved. In this article, we describe two cases of HES involving the middle ear and lung. In both cases, the histological pictures showed an increase of eosinophils in the tissue of the tympanic cavity.