Diagnosis and Management of Hypothyroidism: Addressing the Knowledge-Action Gaps

被引：6
|
作者：
Kalra, Sanjay [1 ]
Das, A. K. [2 ]
Bajaj, Sarita [3 ]
Saboo, Banshi [4 ]
Khandelwal, Deepak [5 ]
Tiwaskar, Mangesh [6 ]
Agarwal, Navneet [7 ]
Gupta, Pritam [8 ]
Sahay, Rakesh [9 ]
Aggarwal, Sameer [10 ]
Ghosh, Sujoy [11 ]
Negalur, Vijay [12 ]
Unnikrishnan, A. G. [13 ]
Bantwal, Ganapathi [14 ]
Aggarwal, Rashmi [15 ]
Chaudhari, Harshal [16 ]
Mulgaonkar, Nitin [16 ]
机构：
[1] Bharti Hosp, Dept Endocrinol, Karnal, Haryana, India
[2] JIPMER, Dept Med, Pondicherry, India
[3] MLN Med Coll, Dept Med, Allahabad, Uttar Pradesh, India
[4] Diacare, Dept Med, Ahmadabad, Gujarat, India
[5] Maharaja Agrasen Hosp, Dept Endocrinol, Delhi, India
[6] Shilpa Med Res Ctr, Dept Med, Bombay, Maharashtra, India
[7] Diabet Obes & Thyroid Ctr, Dept Med, Gwalior, Madhya Pradesh, India
[8] Dr Pritam Guptas Clin, Dept Med, New Delhi, India
[9] Osmania Med Coll & Hosp, Dept Endocrinol, Hyderabad, Telangana, India
[10] PGIMS, Dept Endocrinol, Rohtak, Haryana, India
[11] IGPGMR, Dept Endocrinol, Kolkata, W Bengal, India
[12] Diabet & Thyroid Special Ctr, Dept Med, Thana, Maharashtra, India
[13] Chellaram Diabet Inst, Pune, Maharashtra, India
[14] St Johns Med Coll, Dept Endocrinol, Bengaluru, Karnataka, India
[15] Inst Nucl Med & Allied Sci, Dept Thyroid & Endocrine Res, New Delhi, India
[16] Merck Ltd India, Godrej One,8th Floor,Eastern Express Highway, Bombay 400079, Maharashtra, India
来源：
ADVANCES IN THERAPY | 2018年 / 35卷 / 10期
关键词：
Hypothyroidism; Levothyroxine; Patient-centered approach; Sick day management; Subclinical hypothyroidism (SH); Thyroid-stimulating hormone (TSH); AMERICAN THYROID ASSOCIATION; SUBCLINICAL HYPOTHYROIDISM; CONGENITAL HYPOTHYROIDISM; BIOTIN INTERFERES; DRUG-INTERACTION; PREGNANCY; CANCER; CHILDREN; HORMONE; INDIA;
D O I：
10.1007/s12325-018-0744-7
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Hypothyroidism presents a large epidemiological burden in India. As a result of subtle and nonspecific clinical symptoms and signs, the condition often goes undiagnosed and is not adequately treated when it is detected. There is heterogeneity in the diagnostic and treatment approaches to hypothyroidism. As a result of the physiological changes in thyroid hormones with age and illness, it is important to tailor the diagnosis and management of this condition in specific populations including pregnant women, infants, children, geriatric patients, and those with comorbid conditions. Enhanced understanding and education of physicians and patients can help to improve the outcomes of treatment in hypothyroidism which should be focused on patient-centered care. Policies and reforms should be crafted and implemented at the national level to curb public health challenges of hypothyroidism. This publication summarizes the recommendations of a national advisory board meeting to identify and bridge the gaps in understanding of the diagnosis and treatment of hypothyroidism in India. As a complement to clinical judgment, these recommendations will foster the diagnosis and management of hypothyroidism in the community and clinics for the benefit of the patients.FundingMerck Ltd, India.
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页码：1519 / 1534
页数：16
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