Insights from the molecular docking analysis of colistin with the PmrA protein model from Acinetobacter baumannii

被引:1
|
作者
Ganeshan, Shalini [1 ]
Shakibaie, Mohammad Reza [2 ,3 ]
Rajagopal, Rajaguru [4 ]
机构
[1] Tips Coll Arts & Sci, Dept Biotechnol, Coimbatore 641107, Tamil Nadu, India
[2] Kerman Univ Med Sci, Dept Microbiol & Virol, Kerman, Iran
[3] Kerman Univ Med Sci, Environm Hlth Engn Res Ctr, Kerman, Iran
[4] Mother Theresa Post Grad & Res Inst Hlth Sci, Dept Pharmaceut, Pondicherry 605006, India
关键词
Acinetobacter baumannii; protein modeling; model quality; molecular docking; RESISTANCE;
D O I
10.6026/97320630018041
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Acinetobacter baumannii (AB) is one of the most common causes of nosocomial infections. Therefore, it is of interest to design and develop drugs against Acinetobacter baumannii. A strain of AB showing MIC 32 mu g/ml against colistin was isolated from a hospital environment in Iran. Hence, we document data to glean insights from the molecular docking analysis of colistin with the PmrA protein from this bacterium.
引用
收藏
页码:41 / 49
页数:9
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