A Novel Synthetic Method for the Preparation of Aliphatic Aldehydes from the Corresponding Carboxylic Acids

被引：3
|
作者：
Guo Yuan [1 ,2 ]
Lu Zhenhuan [2 ]
Yao Libo [1 ]
Shi Zhen [2 ]
机构：
[1] Fourth Mil Med Univ, Dept Biochem & Mol Biol, Xian 710032, Shaanxi, Peoples R China
[2] NW Univ Xian, Coll Chem & Mat Sci, Xian 710069, Shaanxi, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2011年 / 29卷 / 03期
基金：
中国博士后科学基金; 中国国家自然科学基金;
关键词：
aliphatic aldehydes; 1,3-dimethylbenzimidazolium salts; reduction; sodium; synthetic method; ALCOHOLS; KETONES; REDUCTION; OXIDATION; CATALYST; HYDRIDE;
D O I：
10.1002/cjoc.201190110
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel synthetic method for the preparation of aliphatic aldehydes from the corresponding carboxylic acids via 1,3-dimethylbenzimidazolium salts is provided. 1,3-Dimethylbenzimidazolium salts were rapidly reduced with sodium/ethanol and then hydrolyzed with hydrochloric acid to obtain aliphatic aldehydes, in which the 1,3-dimethylbenzimidazolium salts can be readily achieved from the corresponding carboxylic acids. The mechanism for the reductive reaction of 1,3-dimethylbenzimidazolium salts with sodium/ethanol was discussed.
引用
收藏
页码：489 / 492
页数：4
相关论文
共 50 条
  • [11] Cutoff in detection of eye irritation from vapors of homologous carboxylic acids and aliphatic aldehydes
    Cometto-Muniz, J. E.
    Cain, W. S.
    Abraham, M. H.
    Sanchez-Moreno, R.
    NEUROSCIENCE, 2007, 145 (03) : 1130 - 1137
  • [12] NEW METHOD FOR PREPARATION OF CARBOXYL-LABELLED ALIPHATIC CARBOXYLIC-ACIDS
    SZABOLCS, A
    SZAMMER, J
    NOSZKO, L
    TETRAHEDRON, 1974, 30 (19) : 3647 - 3648
  • [13] A selective method for the preparation of aliphatic methyl esters in the presence of aromatic carboxylic acids
    Rodríguez, A
    Nomen, M
    Spur, BW
    Godfroid, JJ
    TETRAHEDRON LETTERS, 1998, 39 (47) : 8563 - 8566
  • [14] Direct hydrogenation of carboxylic acids to corresponding aldehydes catalyzed by palladium complexes
    Nagayama, K
    Shimizu, I
    Yamamoto, A
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2001, 74 (10) : 1803 - 1815
  • [15] THE SYNTHESIS OF ALDEHYDES FROM CARBOXYLIC ACIDS
    MOSETTIG, E
    ORGANIC REACTIONS, 1954, 8 : 218 - 257
  • [16] PREPARATION OF METHINE HOMOLOGS OF ALDEHYDES AND CARBOXYLIC-ACIDS
    ZIMMERMANN, B
    LERCHE, H
    SEVERIN, T
    CHEMISCHE BERICHTE-RECUEIL, 1986, 119 (09): : 2848 - 2858
  • [17] A novel approach in cinnamic acid synthesis: Direct synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids in the presence of boron tribromide
    Chiriac, CI
    Tanasa, F
    Onciu, M
    MOLECULES, 2005, 10 (02): : 481 - 487
  • [18] A new direct synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids in the presence of sodium borohydride
    Chiriac, CI
    Tanasa, F
    Onciu, M
    TETRAHEDRON LETTERS, 2003, 44 (17) : 3579 - 3580
  • [19] A safe and affordable method for preparing homologated carboxylic acids from aldehydes
    Snowden, Timothy S.
    Cafiero, Lauren R.
    Lichtenstein, Giora
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [20] REACTION OF CARBOXYLIC ALKYLCARBONIC ANHYDRIDES WITH DISODIUM TETRACARBONYLFERRATE - NOVEL METHOD CONVERTING CARBOXYLIC-ACIDS TO ALDEHYDES
    WATANABE, Y
    YAMASHITA, M
    MITSUDO, TA
    IGAMI, M
    TOMI, K
    TAKEGAMI, Y
    TETRAHEDRON LETTERS, 1975, (12) : 1063 - 1064
12345