Cutaneous leishmaniasis infection in Balb/c mice using a Leishmania tropica strain isolated from Turkey

被引：0
|
作者：
Girginkardesler, N [1 ]
Balcioglu, IC
Yereli, K
Özbilgin, A
Özbel, Y
机构：
[1] Celal Bayar Univ, Sch Med, Dept Parasitol, TR-45010 Manisa, Turkey
[2] Ege Univ, Sch Med, Dept Parasitol, Izmir, Turkey
来源：
JOURNAL OF PARASITOLOGY | 2001年 / 87卷 / 05期
关键词：
D O I：
10.2307/3285257
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Leishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 x 10(7)) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously into the footpads of 10 Balb/c mice. Cutaneous leishmaniasis developed on the footpads of 4 mice approximately 45 days later. Leishmania tropica amastigotes were observed in smear slides and then cultivated in NNN medium. Balb/c mice are a suitable laboratory model for this isolate of L. tropica and thus a source of amastigotes for studies on the immunology, chemotherapy, and pathogenicity of cutaneous leishmaniasis.
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收藏
页码：1177 / 1178
页数：2
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