Targeting malaria parasite proteins to the erythrocyte

被引：25
|
作者：
Templeton, TJ [1 ]
Deitsch, KW [1 ]
机构：
[1] Cornell Univ, Weill Med Coll, Dept Microbiol & Immunol, New York, NY 10021 USA
来源：
TRENDS IN PARASITOLOGY | 2005年 / 21卷 / 09期
关键词：
D O I：
10.1016/j.pt.2005.07.006
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The intraerythrocytic stages of the protozoan parasite Plasmodium falciparum reside within a parasitophorous vacuole (PV) and set up unique 'extraparasite, intra-erythrocyte' protein-trafficking pathways that target parasite-encoded proteins to the erythrocyte cytoplasm and cell surface. Two recent articles report the identification of trafficking motifs that regulate the transport of parasite-encoded proteins across the PV. These articles greatly aid the annotation of the parasite 'secretome' catalog of proteins that are targeted to the erythrocyte cytoplasm or cell membrane.
引用
收藏
页码：399 / 402
页数：4
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