High-throughput drug discovery: what can we exulect from HTS?

被引：124
|
作者：
Gribbon, P [1 ]
Sewing, A [1 ]
机构：
[1] Pfizer Global Res & Dev, Lab Discovery Technol, Sandwich CT13 9NJ, Kent, England
来源：
DRUG DISCOVERY TODAY | 2005年 / 10卷 / 01期
关键词：
D O I：
10.1016/S1359-6446(04)03275-1
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：17 / 22
页数：6
相关论文
共 50 条
  • [41] Mechanism-based high-throughput screening (HTS) for the discovery of novel anticancer drugs
    Aherne, W
    Hardcastle, A
    Newbatt, Y
    Rowlands, M
    Lee, D
    Richards, J
    Stimson, L
    Boxall, K
    Rogers, P
    Workman, P
    EUROPEAN JOURNAL OF CANCER, 2002, 38 : S134 - S134
  • [42] High-Throughput drug discovery of novel inhibitors of secretion.
    Satoh, A.
    Suzuki, H.
    Honjo, Y.
    Nishina, Y.
    MOLECULAR BIOLOGY OF THE CELL, 2014, 25
  • [43] High-throughput X-ray crystallography for drug discovery
    Blundell, TL
    Patel, S
    CURRENT OPINION IN PHARMACOLOGY, 2004, 4 (05) : 490 - 496
  • [44] Development of a Zebrafish Sepsis Model for High-Throughput Drug Discovery
    Anju M. Philip
    Youdong Wang
    Antonio Mauro
    Suzan El-Rass
    John C. Marshall
    Warren L. Lee
    Arthur S. Slutsky
    Claudia C. dos Santos
    Xiao-Yan Wen
    Molecular Medicine, 2017, 23 : 134 - 148
  • [45] Editorial: The protagonism of bioanalytical methods in high-throughput drug discovery
    de Moraes, Marcela Cristina
    de Almeida, Fernando Goncalves
    Tinoco, Luzineide Wanderley
    FRONTIERS IN ANALYTICAL SCIENCE, 2023, 3
  • [46] High-throughput mass spectrometry for compound characterization in drug discovery
    Brönstrup, M
    MODERN MASS SPECTROMETRY, 2003, 225 : 283 - 302
  • [47] Yeast Genomics Technique for High-Throughput Drug Target Discovery
    Sun, Zijun
    Sun, Yanyan
    Zhou, Yaxian
    Wan, Yakun
    DRUG DEVELOPMENT RESEARCH, 2012, 73 (07) : 398 - 405
  • [48] High-Throughput Native Mass Spectrometry Screening in Drug Discovery
    Gavriilidou, Agni F. M.
    Sokratous, Kleitos
    Yen, Hsin-Yung
    De Colibus, Luigi
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2022, 9
  • [49] High-throughput x-ray techniques and drug discovery
    Jhoti, H
    SMALL MOLECULE-PROTEIN INTERACTIONS, 2003, 42 : 43 - 58
  • [50] Contribution of high-throughput docking to the drug discovery process.
    Vangrevelinghe, E
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U773 - U773
12345