Antibiotic susceptibility testing (agar disk diffusion and agar dilution) of clinical isolates of Corynebacterium jeikeium

被引：12

作者：

Traub, WH ^{[1
]}

Geipel, U ^{[1
]}

Leonhard, B ^{[1
]}

Bauer, D ^{[1
]}

机构：

[1] Univ Saarlandes, Inst Med Mikrobiol & Hyg, D-66421 Homburg, Germany

来源：

CHEMOTHERAPY | 1998年 / 44卷 / 04期

关键词：

agar dilution test; agar disk diffusion (Bauer-Kirby) test; antibiotic susceptibility; Corynebacterium jeikeium; minimal inhibitory concentrations; Mueller-Hinton agar; Wilkins-Chalgren agar;

D O I：

10.1159/000007119

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Thirty-three clinical isolates of Corynebacterium jeikeium were examined for susceptibility to 27 antimicrobial drugs with the agar dilution test. Sheep-blood-supplemented Mueller-Hinton agar performed better than Wilkins-Chalgren agar. Disk susceptibility (Bauer-Kirby) tests were carried out in parallel with 24 of the chemotherapeutic agents. All isolates were susceptible to teicoplanin and vancomycin. All isolates resisted fosfomycin, mupirocin, and trimethoprim-sulfamethoxazole. The isolates varied in susceptibility to ciprofloxacin, doxycycline, fusidic acid, ofloxacin, and tetracycline; most were susceptible to rifampin. Surprisingly few discrepancies between agar dilution and disk diffusion tests were encountered when utilizing NCCLS interpretive criteria currently valid for enterococcal isolates.

引用

页码：230 / 237

页数：8

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