Antibiotic susceptibility testing (agar disk diffusion and agar dilution) of clinical isolates of Corynebacterium jeikeium

被引：12
|
作者：
Traub, WH [1 ]
Geipel, U [1 ]
Leonhard, B [1 ]
Bauer, D [1 ]
机构：
[1] Univ Saarlandes, Inst Med Mikrobiol & Hyg, D-66421 Homburg, Germany
来源：
CHEMOTHERAPY | 1998年 / 44卷 / 04期
关键词：
agar dilution test; agar disk diffusion (Bauer-Kirby) test; antibiotic susceptibility; Corynebacterium jeikeium; minimal inhibitory concentrations; Mueller-Hinton agar; Wilkins-Chalgren agar;
D O I：
10.1159/000007119
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Thirty-three clinical isolates of Corynebacterium jeikeium were examined for susceptibility to 27 antimicrobial drugs with the agar dilution test. Sheep-blood-supplemented Mueller-Hinton agar performed better than Wilkins-Chalgren agar. Disk susceptibility (Bauer-Kirby) tests were carried out in parallel with 24 of the chemotherapeutic agents. All isolates were susceptible to teicoplanin and vancomycin. All isolates resisted fosfomycin, mupirocin, and trimethoprim-sulfamethoxazole. The isolates varied in susceptibility to ciprofloxacin, doxycycline, fusidic acid, ofloxacin, and tetracycline; most were susceptible to rifampin. Surprisingly few discrepancies between agar dilution and disk diffusion tests were encountered when utilizing NCCLS interpretive criteria currently valid for enterococcal isolates.
引用
收藏
页码：230 / 237
页数：8
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