Opioids for Chronic Noncancer Pain: Still No Evidence for Superiority of Sustained-Release Opioids

被引：4
|
作者：
Pedersen, L. [1 ,2 ,3 ]
Fredheim, O. M. S. [1 ,2 ,4 ]
机构：
[1] Natl Competence Ctr Complex Symptom Disorders, Trondheim, Norway
[2] Norwegian Univ Sci & Technol, Fac Med, Dept Circulat & Med Imaging, N-7034 Trondheim, Norway
[3] Sorlandet Hosp Kristiansand, Dept Internal Med, Kristiansand, Norway
[4] Akershus Univ Hosp, Ctr Palliat Med, Lorenskog, Norway
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2015年 / 97卷 / 02期
关键词：
SHORT-ACTING OPIOIDS;
D O I：
10.1002/cpt.26
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Opioids are controversial in the treatment of chronic pain due to the risk of addiction, misuse, and death. Long-acting formulations of opioids have been hypothesized to improve pain relief, sleep quality, and lower the risk of side effects and addiction compared to short-acting formulations of opioids. Thus, several guidelines have recommended the use of long-acting opioid formulations over short-acting ones in the treatment of chronic noncancer pain. However, is there really evidence of their superiority?
引用
收藏
页码：114 / 115
页数：2
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