HDAC8 Promotes MLL-Rearranged Acute Myeloid Leukemia By Inhibiting p53 Acetylation

被引：1

作者：

Wu, Dijiong ^{[1
,2
]}

Li, Man ^{[1
]}

Zhang, Lianjun ^{[1
]}

Qi, Jing ^{[1
]}

Chen, Chun-Wei David ^{[3
]}

He, Xin ^{[1
]}

Zhu, Yinghui ^{[1
]}

Dong, Haojie ^{[1
]}

Sun, Jie ^{[1
]}

Li, Ling ^{[1
]}

Marcucci, Guido ^{[1
]}

Kuo, Ya-Huei ^{[1
]}

机构：

[1] City Hope Natl Med Ctr, Hematol Malignancies & Stem Cell Transplantat Ins, Dept Hematol Malignancies Translat Sci, Gehr Family Ctr Leukemia Res,Beckman Res Inst, Duarte, CA USA

[2] Zhejiang Chinese Med Univ, Affiliated Hosp 1, Dept Hematol, Hangzhou, Zhejiang, Peoples R China

[3] City Hope Natl Med Ctr, Beckman Res Inst, Dept Syst Biol, 1500 E Duarte Rd, Duarte, CA 91010 USA

来源：

BLOOD | 2019年 / 134卷

关键词：

D O I：

10.1182/blood-2019-124134

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

642

引用

页数：3

共 50 条

[21] Inhibition Of Telomerase Is a Novel and Effective Therapy In MLL-Rearranged Acute Myeloid Leukemia (AML)
Bruedigam, Claudia
Bagger, Frederik Otzen
Kuhn, Catherine Paine
Therese Vu
Austin, Rebecca
Heidel, Florian H.
Bullinger, Lars
Hill, Geoff R.
Armstrong, Scott A.
Williams, David A.
Lane, Steven W.
BLOOD, 2013, 122 (21)
[22] MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia
Chen, Yufei
Anastassiadis, Konstantinos
Kranz, Andrea
Stewart, A. Francis
Arndt, Kathrin
Waskow, Claudia
Yokoyama, Akihiko
Jones, Kenneth
Neff, Tobias
Lee, Yoo
Ernst, Patricia
CANCER CELL, 2017, 31 (06) : 755 - +
[23] Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia
Chen, Yufei
Jones, Kenneth L.
Anastassiadis, Konstantinos
Kranz, Andrea
Stewart, A. Francis
Grembecka, Jolanta
Meyerson, Matthew
Ernst, Patricia
EXPERIMENTAL HEMATOLOGY, 2019, 69 : 37 - 42
[24] MLL2 PROMOTES CELL SURVIVAL IN MLL1-REARRANGED ACUTE MYELOID LEUKEMIA
不详
CANCER DISCOVERY, 2017, 7 (08) : 795 - 795
[25] Transcription factor MEF2D is required for the maintenance of MLL-rearranged acute myeloid leukemia
Zhao, Lianzhong
Zhang, Pengcheng
Galbo, Phillip M.
Zhou, Xinyue
Aryal, Sajesan
Qiu, Shaowei
Zhang, Hao
Zhou, Yang
Li, Chunliang
Zheng, Deyou
Bhatia, Ravi
Lu, Rui
BLOOD ADVANCES, 2021, 5 (22) : 4727 - 4740
[26] The inhibitory effect of a novel DOT1L inhibitor in MLL-rearranged acute myeloid leukemia
Liu, Wei
Liu, Wei
Deng, Lisheng
Song, Yongcheng
Redell, Michele
Redell, Michele
CANCER RESEARCH, 2013, 73
[27] Effective Targeting of the P53-MDM2 Axis in Preclinical Models of Infant MLL-Rearranged Acute Lymphoblastic Leukemia
Richmond, Jennifer
Carol, Hernan
Evans, Kathryn
High, Laura
Mendomo, Agnes
Robbins, Alissa
Meyer, Claus
Venn, Nicola C.
Marschalek, Rolf
Henderson, Michelle
Sutton, Rosemary
Kurmasheva, Raushan T.
Kees, Ursula R.
Houghton, Peter J.
Smith, Malcolm A.
Lock, Richard B.
CLINICAL CANCER RESEARCH, 2015, 21 (06) : 1395 - 1405
[28] Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia
Ghisi, Margherita
Kats, Lev
Masson, Frederick
Li, Jason
Kratina, Tobias
Vidacs, Eva
Gilan, Omer
Doyle, Maria A.
Newbold, Andrea
Bolden, Jessica E.
Fairfax, Kirsten A.
de Graaf, Carolyn A.
Firth, Matthew
Zuber, Johannes
Dickins, Ross A.
Corcoran, Lynn M.
Dawson, Mark A.
Belz, Gabrielle T.
Johnstone, Ricky W.
CANCER CELL, 2016, 30 (01) : 59 - 74
[29] Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair
Ye, Jing
Zha, Jie
Shi, Yuanfei
Li, Yin
Yuan, Delin
Chen, Qinwei
Lin, Fusheng
Fang, Zhihong
Yu, Yong
Dai, Yun
Xu, Bing
CLINICAL EPIGENETICS, 2019, 11 (01)
[30] FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD+ acute myeloid leukemia
Long, Jun
Jia, Ming-Yuan
Fang, Wei-Yue
Chen, Xin-Jie
Mu, Li-Li
Wang, Zhong-Yu
Shen, Yan
Xiang, Ru-Fang
Wang, Li-Ning
Wang, Ling
Jiang, Chuan-He
Jiang, Jie-Ling
Zhang, Wen-Jun
Sun, Yi-Dan
Chang, Li
Gao, Wen-Hui
Wang, Ying
Li, Jun-Min
Hong, Deng-Li
Liang, Ai-Bin
Hu, Jiong
BLOOD, 2020, 135 (17) : 1472 - 1483

← 1 2 3 4 5 →