Inner segment/Outer segment junction as prognostic factor in macular surgery

Purpose: The aim of the study was to clarify whether an additional information about anatomical and functional prognosis can be made in different macular pathologies by means of high definition optical coherence tomography (OCT). Method: In this retrospective study all cases of surgical therapeutic interventions on the macula, conducted in KH Hietzing between July 2008 and July 2009, were analyzed regarding post operative visual acuity and course in OCT. Visual acuity and central retinal thickness in OCT were compared preoperatively to one month postoperative, as well as visual acuity after 3 months. 45 eyes were subdivided according to their pathology in: 19 eyes (42.2%) with epiretinal fibrosis (ERF), 8 (17.8%) with vitreomacular traction (VMT), 10 (22.2%) with full thickness macular hole (ML) and 8 (17.8%) with lamellar macular hole or pseudohole. The authors discuss one type of general forward-backward stochastic differential equations (FBSDEs) with It's stochastic delayed equations as the forward equations and anticipated backward stochastic differential equations as the backward equations. The existence and uniqueness results of the general FBSDEs are obtained. In the framework of the general FBSDEs in this paper, the explicit form of the optimal control for linearquadratic stochastic optimal control problem with delay and the Nash equilibrium point for nonzero sum differential games problem with delay are obtained. Patients with ERF, who showed a continuous IS/OS-junction in the OCT at the last checkup, showed preand postoperatively better visual acuity (0.41 +/- 0.20 vs. 0.27 +/- 0.11, p = 0.084 and 0.58 +/- 0.22 vs. 0.38 +/- 0.15, p = 0.053). Furthermore, patients with VMT (0.52 +/- 0.22 vs. 0.36 +/- 0.18, p = 0.310) and patients with lamellar macular holes or pseudoholes (0.45 +/- 0.07 vs. 0.66 +/- 0.24, p = 0.137) tended to greater visual gain. The authors discuss one type of general forward-backward stochastic differential equations (FBSDEs) with It's stochastic delayed equations as the forward equations and anticipated backward stochastic differential equations as the backward equations. The existence and uniqueness results of the general FBSDEs are obtained. In the framework of the general FBSDEs in this paper, the explicit form of the optimal control for linearquadratic stochastic optimal control problem with delay and the Nash equilibrium point for nonzero sum differential games problem with delay are obtained. Conclusion: The postoperative course after macular surgery can be monitored more objectively and precisely with the help of high resolution OCT, whereby a more reliable prediction concerning visual acuity in relation with continuous IS/OS-junction can be made.