Synthesis, spectral and antimicrobial evaluation of some new 8-membered phosphorus heterocyclic compounds

被引：0

作者：

Kumar, KA ^{[1
]}

Reddy, CS ^{[1
]}

Reddy, CD ^{[1
]}

机构：

[1] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2003年 / 42卷 / 10期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several new 8-membered phosphours heterocyclic compounds such as 2,10-dichloro-6-aryloxy/arylthio-12-trichloromethyl-12H-dibenzo[d,g][1,3,2]dioxaphosphocin-6-sulfides 4a-i have been synthesized by the cyclocondensation of 2,2-bis(2-hydroxy-5-chlorophenyl) 1,1,1-trichloroethane 1 with thiophosphorylchloride 2 in the presence of base in dry toluene followed by addition of different phenols/thiophenols. The chemical structures of all the products are confirmed by analytical, IR, NMR (H-1, C-13 & P-31) and mass spectral studies. Their bio-assay showed them to possess significant antibacterial and antifungal activity.

引用

页码：2589 / 2594

页数：6

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