Clinical characteristics of schizotypal-related obsessive-compulsive disorder

被引:42
|
作者
Poyurovsky, Michael [1 ,2 ]
Faragian, Sarit [1 ]
Pashinian, Artashez [1 ]
Heidrach, Lilah [1 ]
Fuchs, Camil [3 ]
Weizman, Ronit [4 ,6 ]
Koran, Lorrin [5 ]
机构
[1] Tirat Carmel Mental Hlth Ctr, Res Unit, IL-30200 Tirat Carmel, Israel
[2] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel
[3] Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Dept Stat & Operat Res, IL-69978 Tel Aviv, Israel
[4] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
[5] Stanford Univ, Med Ctr, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA
[6] Tel Aviv Community Mental Hlth Ctr, Tel Aviv, Israel
关键词
schizotypal personality disorder; obsessive-compulsive disorder; schizophrenia spectrum disorders;
D O I
10.1016/j.psychres.2007.02.019
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
In this study we compared 15 patients with DSM-IV obsessive-compulsive disorder (OCD) and schizotypal personality disorder (SPD) and 31 non-SPD OCD patients. OCD-SPD patients had poorer insight, more negative symptoms, lower functioning, more antipsychotic augmentation and more first-degree relatives with schizophrenia-spectrum disorders. A distinct clinical phenotype of OCD associated with SPD should be considered when investigating etiopathogenetic mechanisms. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:254 / 258
页数:5
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